Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.57 |
| ▸ | MAPT | P10636 | 6/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.57 |
| ▸ | MEN1 | O00255 | 5/20 | 0.57 |
| ▸ | THRB | P10828 | 3/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.57 |
| ▸ | RECQL | P46063 | 2/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.57 |
| ▸ | POLB | P06746 | 2/20 | 0.57 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.57 |
| ▸ | CASP1 | P29466 | 2/20 | 0.57 |
| ▸ | CASP7 | P55210 | 2/20 | 0.57 |
| ▸ | USP2 | O75604 | 2/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.57 |
| ▸ | PKM | P14618 | 1/20 | 0.57 |
| ▸ | APEX1 | P27695 | 1/20 | 0.57 |
| ▸ | BLM | P54132 | 1/20 | 0.57 |
| ▸ | TNF | P01375 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13985596 | 0.84 | ALDH1A1 (0.57) | KDM4EMAPTKMT2ATDP1ALDH1A1 | |
| SCHEMBL19050355 | 0.78 | MEN1 (0.47) | KDM4EMAPTKMT2ATDP1ALDH1A1 | |
| SCHEMBL11145898 | 0.78 | MEN1 (0.61) | MAPTKMT2ATDP1ALDH1A1MEN1 | |
| SCHEMBL231377 | 0.76 | ALDH1A1 (0.68) | KDM4EMAPTKMT2ATDP1ALDH1A1 | |
| SCHEMBL29364937 | 0.76 | ALDH1A1 (0.68) | KDM4EMAPTKMT2ATDP1ALDH1A1 | |
| SCHEMBL28238985 | 0.76 | KDM4E (0.55) | KDM4EMAPTKMT2ATDP1ALDH1A1 | |
| SCHEMBL3186264 | 0.76 | MAPT (0.39) | KDM4EMAPTKMT2ATDP1ALDH1A1 | |
| SCHEMBL9892495 | 0.76 | CSNK2A1 (0.57) | KDM4EKMT2AALDH1A1MEN1POLB | |
| SCHEMBL13081781 | 0.76 | KEAP1 (0.55) | KDM4EMAPTKMT2ATDP1ALDH1A1 | |
| SCHEMBL16310776 | 0.76 | ALDH1A1 (0.40) | KDM4EMAPTKMT2ATDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9833425-B2 | Gentisic acid is used to improve systemic hemodynamics, hepatic mitochondrial function and lactate acidemia in patients with septic shock | UNIVERSITY OF MANITOBA (CA) | 2017-12-05 | — | — | US | disclosed |