Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.55 |
| ▸ | GLA | P06280 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | POLB | P06746 | 3/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | MYC | P01106 | 1/20 | 0.46 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.46 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.45 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.45 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.45 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.45 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | CES2 | O00748 | 1/20 | 0.44 |
| ▸ | GALR3 | O60755 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19500335 | 0.84 | KDM4E (0.50) | KDM4EGLAMAPTPOLBMAPK1 | |
| SCHEMBL14435758 | 0.82 | PTGDR2 (0.46) | KDM4EGLAMAPTPOLBMAPK1 | |
| SCHEMBL19050355 | 0.78 | MEN1 (0.47) | KDM4EMAPTMYCHPGDCYP1A2 | |
| SCHEMBL11145898 | 0.78 | MEN1 (0.61) | MAPTPOLBMYCCES2MEN1 | |
| SCHEMBL618056 | 0.76 | KDM4E (0.65) | KDM4EGLAMYCNR4A1GRIN1 | |
| SCHEMBL9892495 | 0.76 | CSNK2A1 (0.57) | KDM4EPOLBMEN1KMT2AALDH1A1 | |
| SCHEMBL13081781 | 0.76 | KEAP1 (0.55) | KDM4EMAPTHPGDCES2CYP2C19 | |
| SCHEMBL3186264 | 0.76 | MAPT (0.39) | KDM4EMAPTPOLBMAPK1HPGD | |
| SCHEMBL19670802 | 0.76 | KDM4E (0.57) | KDM4EGLAMAPTPOLBHPGD | |
| SCHEMBL28237983 | 0.74 | ALDH1A1 (0.50) | MAPTMAPK1HPGDMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108484541-A | A kind of synthetic method of 5- formylfurans -2- ethyl nitrobenzoates | 济南大学 | 2018-09-04 | — | — | CN | claimed |
| CN-108484541-A | A kind of synthetic method of 5- formylfurans -2- ethyl nitrobenzoates | 济南大学 | 2018-09-04 | — | — | CN | disclosed |