Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17084921 | 0.89 | CHRNB2 (0.32) | — | |
| SCHEMBL15428249 | 0.83 | KDM4E (0.36) | KDM4ELMNATP53POLBMAPT | |
| SCHEMBL15427818 | 0.81 | KDM4E (0.32) | KDM4ELMNATP53POLBMAPT | |
| SCHEMBL15427718 | 0.76 | — | — | |
| SCHEMBL15427943 | 0.70 | CCR1 (0.35) | KDM4ELMNATP53POLBMAPT | |
| SCHEMBL15427720 | 0.68 | — | — | |
| SCHEMBL18309506 | 0.66 | KDM4E (0.37) | KDM4ELMNATP53POLBMAPT | |
| SCHEMBL15840891 | 0.66 | PGR (0.39) | KDM4ELMNAPOLBMAPTHSD17B10 | |
| SCHEMBL19670892 | 0.65 | PRKDC (0.42) | KDM4ETP53POLBMAPT | |
| SCHEMBL15427721 | 0.65 | PDE2A (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9837622-B2 | Metal complexes | MERCK PATENT GMBH (DE) | 2017-12-05 | — | — | US | disclosed |