Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.62 |
| ▸ | LMNA | P02545 | 2/20 | 0.62 |
| ▸ | MAPT | P10636 | 2/20 | 0.62 |
| ▸ | NPC1 | O15118 | 2/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.62 |
| ▸ | HPGD | P15428 | 1/20 | 0.62 |
| ▸ | TDP2 | O95551 | 3/20 | 0.50 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | MMP12 | P39900 | 1/20 | 0.42 |
| ▸ | MMP13 | P45452 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.41 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19847551 | 0.93 | LMNA (0.67) | RAB9ALMNAMAPTNPC1ALDH1A1 | |
| SCHEMBL7139324 | 0.85 | TDP2 (0.58) | RAB9ALMNAMAPTNPC1ALDH1A1 | |
| SCHEMBL29569358 | 0.85 | TDP2 (0.61) | RAB9ALMNAMAPTNPC1ALDH1A1 | |
| SCHEMBL3136254 | 0.85 | TDP2 (0.61) | RAB9ALMNAMAPTNPC1ALDH1A1 | |
| SCHEMBL1482920 | 0.85 | TDP2 (0.61) | RAB9ALMNAMAPTNPC1ALDH1A1 | |
| SCHEMBL1482804 | 0.83 | MAPT (0.57) | RAB9ALMNAMAPTNPC1ALDH1A1 | |
| SCHEMBL30172496 | 0.83 | MAPT (0.57) | RAB9ALMNAMAPTNPC1ALDH1A1 | |
| SCHEMBL1666630 | 0.83 | MAPT (0.57) | RAB9ALMNAMAPTNPC1ALDH1A1 | |
| SCHEMBL30831157 | 0.83 | TDP2 (0.59) | RAB9ALMNAMAPTNPC1ALDH1A1 | |
| SCHEMBL19847534 | 0.83 | KDM4E (0.68) | RAB9ALMNAMAPTNPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3131901-B1 | MATERIALS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2018-02-07 | — | — | EP | disclosed |
| EP-3114102-B1 | MATERIALS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2017-12-06 | — | — | EP | disclosed |