Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 7/20 | 0.52 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.52 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.47 |
| ▸ | JAK2 | O60674 | 1/20 | 0.46 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.42 |
| ▸ | FEN1 | P39748 | 1/20 | 0.42 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.42 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.42 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.42 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.41 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.40 |
| ▸ | CSF1R | P07333 | 1/20 | 0.40 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.40 |
| ▸ | GRM5 | P41594 | 1/20 | 0.39 |
| ▸ | BRS3 | P32247 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28045856 | 0.80 | BCAT2 (0.65) | PARP1PARP2BCAT2CASP1CSF1R | |
| SCHEMBL3529606 | 0.77 | BCAT2 (0.51) | PARP1BCAT2JAK2ALOX5APFEN1 | |
| SCHEMBL1967459 | 0.77 | BCAT2 (0.51) | PARP1BCAT2ALOX5APFEN1CSNK1A1 | |
| SCHEMBL7360342 | 0.77 | BCAT2 (0.51) | PARP1BCAT2ALOX5APFEN1CSNK1A1 | |
| SCHEMBL28317480 | 0.75 | PARP1 (0.43) | PARP1PARP2BCAT2JAK2CSNK1A1 | |
| SCHEMBL25093211 | 0.73 | BCAT2 (0.47) | PARP1BCAT2ALOX5APFEN1CSNK1A1 | |
| SCHEMBL17894102 | 0.73 | KMT2A (0.54) | PARP1BCAT2ALOX5APFEN1CSNK1A1 | |
| SCHEMBL30839549 | 0.73 | PARP1 (0.48) | PARP1BCAT2ALOX5APFEN1CSNK1A1 | |
| SCHEMBL30810258 | 0.73 | KMT2A (0.54) | PARP1BCAT2ALOX5APFEN1CSNK1A1 | |
| SCHEMBL29069180 | 0.73 | BCAT2 (0.44) | PARP1PARP2BCAT2ALOX5APFEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2334652-A1 | 1H-BENZ IMIDAZOLE-5-CARBOXAMIDES AS ANTI-INFLAMMATORY AGENTS | Boehringer Ingelheim International GmbH (DE) | 2011-06-22 | — | — | EP | disclosed |
| EP-1661569-B1 | Compounds effecting glucokinase | ASTRAZENECA AB (SE) | 2008-06-11 | — | — | EP | disclosed |