SCHEMBL28045856

SCHEMBL28045856

N#Cc1ccc(-c2ccccc2C(N)=O)cc1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BCAT2 O15382 1/20 0.65
PARP1 P09874 3/20 0.55
PARP2 Q9UGN5 2/20 0.55
CASP1 P29466 1/20 0.52
IRAK4 Q9NWZ3 1/20 0.50
BRS3 P32247 1/20 0.44
CHEK1 O14757 1/20 0.44
LTB4R2 Q9NPC1 1/20 0.44
PARP15 Q460N3 1/20 0.44
PARP10 Q53GL7 1/20 0.44
CSF1R P07333 1/20 0.43
MAOB P27338 1/20 0.43
MYC P01106 1/20 0.43
GRM2 Q14416 1/20 0.43
KDM4E B2RXH2 2/20 0.42
CYP1A2 P05177 1/20 0.42
CYP2C9 P11712 1/20 0.42
CYP2C19 P33261 1/20 0.42
PDK2 Q15119 1/20 0.41
MMP3 P08254 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5878337 0.85 BCAT2 (0.87) BCAT2PARP1CHEK1LTB4R2KDM4E
SCHEMBL4952744 0.85 BCAT2 (0.62) BCAT2PARP1PARP2CASP1BRS3
SCHEMBL6164290 0.84 BRS3 (0.57) BCAT2BRS3LTB4R2MAOBALDH1A1
SCHEMBL30582476 0.83 BCAT2 (0.83) BCAT2CHEK1LTB4R2KDM4EALDH1A1
SCHEMBL15492872 0.83 BRS3 (0.44) BCAT2PARP1PARP2CASP1IRAK4
SCHEMBL5015475 0.83 LTB4R2 (0.46) BCAT2PARP1PARP2IRAK4BRS3
SCHEMBL11805019 0.83 BRS3 (0.56) BCAT2BRS3LTB4R2PDK2MMP3
SCHEMBL20703692 0.82 BCAT2 (0.59) BCAT2PARP1PARP2CHEK1CSF1R
SCHEMBL11525121 0.80 BRS3 (0.46) BCAT2PARP1PARP2BRS3LTB4R2
SCHEMBL5639723 0.80 BCAT2 (0.61) BCAT2PARP1IRAK4CHEK1LTB4R2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118048636-B Electrocatalytic synthesis method for N-aryl amide 平顶山学院 2024-09-13 CN disclosed
CN-118048636-A Electrocatalytic synthesis method for N-aryl amide 平顶山学院 2024-05-17 CN disclosed
CN-107007587-A For inducing chondrogenetic Compounds and methods for 加州生物医学研究所 2017-08-04 CN disclosed
CN-105228626-A Compounds and methods for inducing chondrogenesis CALIFORNIA INST BIOMEDICAL RES 2016-01-06 CN disclosed