Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM5B | Q9UGL1 | 6/20 | 0.43 |
| ▸ | KDM5C | P41229 | 3/20 | 0.43 |
| ▸ | KDM4A | O75164 | 2/20 | 0.43 |
| ▸ | KDM5A | P29375 | 2/20 | 0.43 |
| ▸ | KDM2B | Q8NHM5 | 2/20 | 0.43 |
| ▸ | KDM6B | O15054 | 1/20 | 0.43 |
| ▸ | KDM1A | O60341 | 7/20 | 0.42 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.40 |
| ▸ | DRD3 | P35462 | 2/20 | 0.39 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.38 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.38 |
| ▸ | NAMPT | P43490 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15636702 | 0.96 | KDM5B (0.46) | KDM5BKDM5CKDM4AKDM5AKDM2B | |
| SCHEMBL15636442 | 0.84 | KDM5B (0.52) | KDM5BKDM5CKDM4AKDM5AKDM2B | |
| SCHEMBL19664330 | 0.82 | KDM1A (0.42) | KDM1ADRD3PDE3BPDE3A | |
| SCHEMBL16291811 | 0.73 | KDM5C (0.51) | KDM5BKDM5CKDM4AKDM5AKDM2B | |
| SCHEMBL15637693 | 0.73 | KDM2B (0.51) | KDM5BKDM5CKDM4AKDM5AKDM2B | |
| SCHEMBL15636980 | 0.73 | KDM5B (0.59) | KDM5BKDM5CKDM4AKDM5AKDM2B | |
| SCHEMBL19676471 | 0.72 | KDM2B (0.42) | KDM5BKDM5CKDM4AKDM5AKDM2B | |
| SCHEMBL17144250 | 0.72 | CYP2D6 (0.46) | KDM5BKDM5CKDM4AKDM5AKDM2B | |
| SCHEMBL15636566 | 0.71 | KDM2B (0.49) | KDM5BKDM5CKDM4AKDM5AKDM2B | |
| SCHEMBL21257720 | 0.71 | KDM4C (0.50) | KDM5BKDM5CKDM5AKDM2BKDM6B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3023415-B1 | INHIBITORS OF HISTONE DEMETHYLASES | GILEAD SCIENCES INC (US) | 2017-12-06 | — | — | EP | disclosed |