Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 4/20 | 0.48 |
| ▸ | GPR84 | Q9NQS5 | 6/20 | 0.42 |
| ▸ | PLA2G1B | P04054 | 3/20 | 0.42 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.42 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | PSMD14 | O00487 | 2/20 | 0.37 |
| ▸ | MMP2 | P08253 | 2/20 | 0.37 |
| ▸ | ATG4B | Q9Y4P1 | 2/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | RAD52 | P43351 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5414617 | 0.96 | DNM1 (0.48) | DNM1GPR84PLA2G1BPLA2G2AFFAR4 | |
| SCHEMBL5408876 | 0.96 | DNM1 (0.48) | DNM1GPR84PLA2G1BPLA2G2AFFAR4 | |
| SCHEMBL5412524 | 0.96 | DNM1 (0.48) | DNM1GPR84PLA2G1BPLA2G2AFFAR4 | |
| SCHEMBL5406861 | 0.96 | DNM1 (0.48) | DNM1GPR84PLA2G1BPLA2G2AFFAR4 | |
| SCHEMBL5412471 | 0.96 | DNM1 (0.48) | DNM1GPR84PLA2G1BPLA2G2AFFAR4 | |
| SCHEMBL5406792 | 0.96 | DNM1 (0.48) | DNM1GPR84PLA2G1BPLA2G2AFFAR4 | |
| SCHEMBL24844337 | 0.95 | DNM1 (0.52) | DNM1GPR84PLA2G1BPLA2G2AFFAR4 | |
| SCHEMBL12515784 | 0.91 | GPR84 (0.46) | GPR84PLA2G1BPLA2G2AFFAR4FFAR1 | |
| SCHEMBL12515911 | 0.91 | GPR84 (0.46) | GPR84PLA2G1BPLA2G2AFFAR4FFAR1 | |
| SCHEMBL19677890 | 0.89 | GPR84 (0.42) | GPR84PLA2G1BPLA2G2AFFAR4FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11685710-B2 | Cationic sulfonamide amino lipids and amphiphilic zwitterionic amino lipids | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2023-06-27 | — | — | US | disclosed |
| US-11685710-B2 | Cationic sulfonamide amino lipids and amphiphilic zwitterionic amino lipids | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2023-06-27 | — | — | US | disclosed |
| US-11542229-B2 | Cationic sulfonamide amino lipids and amphiphilic zwitterionic amino lipids | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2023-01-03 | — | — | US | disclosed |
| US-20210395192-A1 | CATIONIC SULFONAMIDE AMINO LIPIDS AND AMPHIPHILIC ZWITTERIONIC AMINO LIPIDS | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2021-12-23 | — | — | US | disclosed |
| US-20200140378-A1 | CATIONIC SULFONAMIDE AMINO LIPIDS AND AMPHIPHILIC ZWITTERIONIC AMINO LIPIDS | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2020-05-07 | — | — | US | disclosed |
| US-10562849-B2 | Cationic sulfonamide amino lipids and amphiphilic zwitterionic amino lipids | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2020-02-18 | — | — | US | disclosed |
| US-20170349543-A1 | CATIONIC SULFONAMIDE AMINO LIPIDS AND AMPHIPHILIC ZWITTERIONIC AMINO LIPIDS | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2017-12-07 | — | — | US | disclosed |
| US-20170349543-A1 | CATIONIC SULFONAMIDE AMINO LIPIDS AND AMPHIPHILIC ZWITTERIONIC AMINO LIPIDS | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2017-12-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170349543-A1 | CATIONIC SULFONAMIDE AMINO LIPIDS AND AMPHIPHILIC ZWITTERIONIC AMINO LIPIDS | ABHD16A, AARS1, CFTR | DNM1 700/4885GPR84 684/4885PLA2G1B 446/4885 |
| US-10562849-B2 | Cationic sulfonamide amino lipids and amphiphilic zwitterionic amino lipids | ABHD16A, AARS1, CFTR | DNM1 700/4885GPR84 684/4885PLA2G1B 446/4885 |
| US-11685710-B2 | Cationic sulfonamide amino lipids and amphiphilic zwitterionic amino lipids | ABHD16A, AARS1, CFTR | DNM1 700/4885GPR84 684/4885PLA2G1B 446/4885 |
| US-11542229-B2 | Cationic sulfonamide amino lipids and amphiphilic zwitterionic amino lipids | ABHD16A, AARS1, CFTR | DNM1 700/4885GPR84 684/4885PLA2G1B 446/4885 |
| US-20200140378-A1 | CATIONIC SULFONAMIDE AMINO LIPIDS AND AMPHIPHILIC ZWITTERIONIC AMINO LIPIDS | ABHD16A, AARS1, CFTR | DNM1 700/4885GPR84 684/4885PLA2G1B 446/4885 |
| US-20210395192-A1 | CATIONIC SULFONAMIDE AMINO LIPIDS AND AMPHIPHILIC ZWITTERIONIC AMINO LIPIDS | ABHD16A, AARS1, CFTR | DNM1 700/4885GPR84 684/4885PLA2G1B 446/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.