⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8685779 | 0.78 | MAPT (0.35) | — | |
| SCHEMBL452239 | 0.76 | MAPT (0.35) | — | |
| SCHEMBL2203 | 0.76 | NPC1 (0.42) | — | |
| SCHEMBL209284 | 0.76 | NPC1 (0.34) | — | |
| SCHEMBL155050 | 0.73 | MAPT (0.46) | — | |
| SCHEMBL832129 | 0.73 | PNMT (0.39) | — | |
| SCHEMBL293686 | 0.72 | TSHR (0.46) | — | |
| SCHEMBL61310 | 0.69 | CA12 (0.50) | — | |
| SCHEMBL209077 | 0.69 | MAOA (0.38) | — | |
| SCHEMBL2655668 | 0.67 | PLAU (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 18793 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118317956-A | Bis (hetero) aryl thioether oxadiazines as fungicidal compounds | 拜耳公司 | 2024-07-09 | — | — | CN | claimed |
| EP-4385985-A1 | HETEROCYCLIC DERIVATIVE, AND COMPOSITION AND PHARMACEUTICAL USE THEREOF | Xizang Haisco Pharmaceutical Co., Ltd. (CN) | 2024-06-19 | — | — | EP | claimed |
| CN-118102889-A | Organic compound | 奇华顿股份有限公司 | 2024-05-28 | — | — | CN | claimed |
| US-20240101535-A1 | DIHYDROISOQUINOLINONE DERIVATIVE AND APPLICATION THEREOF | ETERN BIOPHARMA (SHANGHAI) CO., LTD. (CN) | 2024-03-28 | — | — | US | claimed |
| US-20240083903-A1 | ARYL ETHER COMPOUNDS AS TEAD MODULATORS | MERCK SHARP & DOHME LLC (US) | 2024-03-14 | — | — | US | claimed |
| WO-2024027694-A1 | PROTEIN DEGRADATION AGENT | 苏州开拓药业股份有限公司 | 2024-02-08 | — | — | WO | claimed |
| CN-111918863-B | Heterocyclic compounds | 武田药品工业株式会社 | 2024-01-05 | — | — | CN | claimed |
| EP-4294382-A1 | ARYL ETHER COMPOUNDS AS TEAD MODULATORS | Merck Sharp & Dohme LLC (US) | 2023-12-27 | — | — | EP | claimed |
| EP-3567041-B1 | SUBSTITUTED FUSED HETEROARYL COMPOUND SERVING AS A KINASE INHIBITOR, AND APPLICATIONS THEREOF | IMPACT THERAPEUTICS SHANGHAI INC (CN) | 2023-12-27 | — | — | EP | claimed |
| US-20230406885-A1 | CYCLIC PEPTIDES FOR TRAPPING INTERLEUKIN-1 BETA | MERCK SHARP & DOHME LLC (US) | 2023-12-21 | — | — | US | claimed |
| US-4678800-A | INHIBITORS OF ANGIOTENSIN-CONVERTING ENZYME | CIBA-GEIGY CORPORATION (US) | 1987-07-07 | — | — | US | claimed |
| EP-0183398-A1 | Angiotensin converting enzyme inhibitors and their production and use as pharmaceuticals | FISONS plc (GB) | 1986-06-04 | — | — | EP | claimed |
| US-4576905-A | Photographically useful chalcogenazoles, chalcogenazolines, and chalcogenazolinium and chalcogenazolium salts | EASTMAN KODAK COMPANY (US) | 1986-03-18 | — | — | US | claimed |
| US-4575483-A | FACILITATE IMAGE FORMATION | EASTMAN KODAK COMPANY (US) | 1986-03-11 | — | — | US | claimed |
| EP-0136847-A2 | Photographically useful chalcogenazolylidene and chalcogenazolium dyes and methods for their preparation | EASTMAN KODAK COMPANY (a New Jersey corporation) (US) | 1985-04-10 | — | — | EP | claimed |
| US-4460594-A | CENTRAL NERVOUS SYSTEM DISORDERS | BEECHAM GROUP P.L.C. (GB) | 1984-07-17 | — | — | US | claimed |
| EP-0077607-A1 | N-substituted 3-aryl piperidines and derivatives thereof | BEECHAM GROUP PLC (GB) | 1983-04-27 | — | — | EP | claimed |
| US-4292238-A | Alkylation of benzthiazole-azo-phenylamine dyestuffs | BAYER AKTIENGESELLSCHAFT (DE) | 1981-09-29 | — | — | US | claimed |
| US-4212803-A | Cationic azo dyestuffs containing oxyalkylene substituent | BAYER AKTIENGESELLSCHAFT (DE) | 1980-07-15 | — | — | US | claimed |
| US-4175956-A | Electrophotosensitive materials for migration imaging processes | EASTMAN KODAK COMPANY (US) | 1979-11-27 | — | — | US | claimed |