Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METTL3 | Q86U44 | 12/20 | 0.39 |
| ▸ | ADK | P55263 | 4/20 | 0.35 |
| ▸ | RAPGEF3 | O95398 | 1/20 | 0.33 |
| ▸ | PRMT5 | O14744 | 3/20 | 0.33 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19679328 | 0.91 | ADK (0.35) | METTL3ADK | |
| SCHEMBL19684891 | 0.90 | PRMT5 (0.38) | METTL3ADKPRMT5WDR77 | |
| SCHEMBL19679329 | 0.85 | PRMT5 (0.39) | PRMT5WDR77 | |
| SCHEMBL30207875 | 0.84 | SRC (0.37) | METTL3 | |
| SCHEMBL19667609 | 0.84 | SRC (0.37) | METTL3 | |
| SCHEMBL19684885 | 0.81 | PRMT5 (0.38) | ADKPRMT5WDR77 | |
| SCHEMBL19679283 | 0.76 | METTL3 (0.45) | METTL3ADKPRMT5WDR77 | |
| SCHEMBL19667699 | 0.76 | MKNK1 (0.37) | ADK | |
| SCHEMBL19684888 | 0.75 | PRMT5 (0.48) | PRMT5WDR77 | |
| SCHEMBL19684667 | 0.74 | PRMT5 (0.50) | METTL3PRMT5WDR77 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170348313-A1 | SUBSTITUTED CARBONUCLEOSIDE DERIVATIVES USEFUL AS ANTICANCER AGENTS | PFIZER INC. (US) | 2017-12-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170348313-A1 | SUBSTITUTED CARBONUCLEOSIDE DERIVATIVES USEFUL AS ANTICANCER AGENTS | DUT, NCL, TYMP | METTL3 918/4885ADK 1317/4885RAPGEF3 3171/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.