Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 5/20 | 0.47 |
| ▸ | IGF1R | P08069 | 3/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.46 |
| ▸ | TYR | P14679 | 1/20 | 0.46 |
| ▸ | LCK | P06239 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.46 |
| ▸ | BACE1 | P56817 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 3/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.45 |
| ▸ | APEX1 | P27695 | 2/20 | 0.45 |
| ▸ | THPO | P40225 | 2/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | BLM | P54132 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21317639 | 0.85 | HTR2B (0.54) | CYP19A1KDM4EMAPTALDH1A1GAA | |
| SCHEMBL19665514 | 0.81 | AKR1B1 (0.61) | ALOX15IGF1RLCKAKR1B1HTR2B | |
| SCHEMBL6174381 | 0.80 | HTR2B (0.54) | MAPTGAAHTR2B | |
| SCHEMBL7959794 | 0.78 | CALM1 (0.57) | ALDH1A1CYP3A4TAAR1 | |
| SCHEMBL18417920 | 0.77 | HTR2B (0.60) | ALOX15CYP19A1TYRKDM4EMAPT | |
| SCHEMBL30631592 | 0.74 | ALOX15 (0.80) | ALOX15IGF1RLCKKDM4EMAPT | |
| SCHEMBL107956 | 0.74 | ALOX15 (0.80) | ALOX15IGF1RLCKKDM4EMAPT | |
| SCHEMBL31733931 | 0.73 | CYP3A4 (0.47) | ALOX15KDM4EMAPTALDH1A1GAA | |
| SCHEMBL4542482 | 0.73 | ALOX15 (0.64) | ALOX15IGF1RCYP19A1TYRLCK | |
| SCHEMBL8431254 | 0.72 | ALOX15 (0.76) | ALOX15IGF1RLCKKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170349548-A1 | P21-ACTIVATED KINASE INHIBITOR | BIOSYSTEM CONSULTING LIMITED COMPANY (JP) | 2017-12-07 | — | — | US | disclosed |
| US-20170349548-A1 | P21-ACTIVATED KINASE INHIBITOR | BIOSYSTEM CONSULTING LIMITED COMPANY (JP) | 2017-12-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170349548-A1 | P21-ACTIVATED KINASE INHIBITOR | HIPK1, CDKN1A, HIPK2 | ALOX15 3381/4885IGF1R 1083/4885CYP19A1 2394/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.