Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2B | P41595 | 4/20 | 0.54 |
| ▸ | HTR3A | P46098 | 1/20 | 0.54 |
| ▸ | HSD17B3 | P37058 | 2/20 | 0.52 |
| ▸ | PPARG | P37231 | 3/20 | 0.51 |
| ▸ | DAO | P14920 | 2/20 | 0.51 |
| ▸ | GPR84 | Q9NQS5 | 4/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | CA3 | P07451 | 1/20 | 0.45 |
| ▸ | CA4 | P22748 | 1/20 | 0.45 |
| ▸ | CA5A | P35218 | 1/20 | 0.45 |
| ▸ | CA7 | P43166 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.45 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.42 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8116893 | 0.90 | HTR2B (0.56) | HTR2BHTR3AHSD17B3PPARGDAO | |
| SCHEMBL21317639 | 0.88 | HTR2B (0.54) | HTR2BHTR3AHSD17B3CA2GAA | |
| SCHEMBL6174115 | 0.84 | HSD17B3 (0.51) | HSD17B3GAAMAPT | |
| SCHEMBL19679883 | 0.80 | ALOX15 (0.47) | HTR2BGAAMAPT | |
| SCHEMBL31733931 | 0.76 | CYP3A4 (0.47) | HSD17B3CA12CA2CA9GAA | |
| Dihydro-5,6-Dehydrokawain SCHEMBL19679894 | 0.76 | PPARG (0.59) | HTR2BHTR3APPARGCA12CA1 | |
| SCHEMBL28489823 | 0.75 | PPARG (0.55) | HTR2BHTR3AHSD17B3PPARGDAO | |
| SCHEMBL3700781 | 0.74 | MEN1 (0.50) | HSD17B3CA9GAAMAPT | |
| SCHEMBL7959794 | 0.74 | CALM1 (0.57) | — | |
| SCHEMBL9026440 | 0.74 | CA12 (0.50) | HTR2BHTR3AHSD17B3PPARGDAO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115011576-B | Aquilaria sinensis-derived III-type polyketide synthase AsPKS, and encoding gene and application thereof | 中国医学科学院药用植物研究所 | 2024-10-25 | — | — | CN | claimed |
| CN-114990084-B | Aquilaria sinensis-derived III-type polyketide synthase AsPKS4, and encoding gene and application thereof | 中国医学科学院药用植物研究所 | 2024-08-23 | — | — | CN | claimed |
| CN-115011576-A | Aquilaria sinensis-derived III-type polyketide synthase AsPKS5, and coding gene and application thereof | 中国医学科学院药用植物研究所 | 2022-09-06 | — | — | CN | claimed |
| CN-114990084-A | Aquilaria sinensis-derived III-type polyketide synthase AsPKS4, and coding gene and application thereof | 中国医学科学院药用植物研究所 | 2022-09-02 | — | — | CN | claimed |
| EP-4702039-A1 | METHOD OF PRODUCING STYRYLPYRONES AND CHALCONES | Nicoventures Trading Limited (GB) | 2026-03-04 | — | — | EP | disclosed |
| WO-2024224080-A1 | METHOD OF PRODUCING STYRYLPYRONES AND CHALCONES | Nicoventures Trading Limited (GB) | 2024-10-31 | — | — | WO | disclosed |
| CN-115011576-B | Aquilaria sinensis-derived III-type polyketide synthase AsPKS, and encoding gene and application thereof | 中国医学科学院药用植物研究所 | 2024-10-25 | — | — | CN | disclosed |
| CN-114990084-B | Aquilaria sinensis-derived III-type polyketide synthase AsPKS4, and encoding gene and application thereof | 中国医学科学院药用植物研究所 | 2024-08-23 | — | — | CN | disclosed |
| CN-115011576-A | Aquilaria sinensis-derived III-type polyketide synthase AsPKS5, and coding gene and application thereof | 中国医学科学院药用植物研究所 | 2022-09-06 | — | — | CN | disclosed |
| CN-114990084-A | Aquilaria sinensis-derived III-type polyketide synthase AsPKS4, and coding gene and application thereof | 中国医学科学院药用植物研究所 | 2022-09-02 | — | — | CN | disclosed |
| US-10941429-B2 | Enzymatic synthesis of kavalactones and flavokavains | WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH (US) | 2021-03-09 | — | — | US | disclosed |
| US-20190271015-A1 | ENZYMATIC SYNTHESIS OF KAVALACTONES AND FLAVOKAVAINS | WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH | 2019-09-05 | — | — | US | disclosed |
| US-6169181-B1 | HUMAN IMMUNODEFICIENCY VIRUS PROTEINASE INHIBITORS | PHARMACIA & UPJOHN COMPANY | 2001-01-02 | — | — | US | disclosed |
| US-6114546-A | Aminomethylene derivatives and ultraviolet absorbent comprising thereof | CHEMIPRO KASEI KAISHA, LIMITED (JP) | 2000-09-05 | — | — | US | disclosed |
| EP-0950655-A1 | AMINOMETHYLENE DERIVATIVES AND ULTRAVIOLET ABSORBER COMPRISING THE SAME | CHEMIPRO KASEI KAISHA, LIMITED (JP) | 1999-10-20 | — | — | EP | disclosed |
| US-5852195-A | Pyranone compounds useful to treat retroviral infections | PHARMACIA & UPJOHN COMPANY (US) | 1998-12-22 | — | — | US | disclosed |
| EP-0758327-A1 | PYRANONE COMPOUNDS USEFUL TO TREAT RETROVIRAL INFECTIONS | PHARMACIA & UPJOHN COMPANY (US) | 1997-02-19 | — | — | EP | disclosed |
| WO-1995030670-A2 | PYRANONE COMPOUNDS USEFUL TO TREAT RETROVIRAL INFECTIONS | PHARMACIA & UPJOHN COMPANY (US) | 1995-11-16 | — | — | WO | disclosed |
| EP-0668860-A1 | PYRAN-2-ONES AND 5,6-DIHYDROPYRAN-2-ONES USEFUL FOR TREATING HIV AND OTHER RETROVIRUSES | PHARMACIA & UPJOHN COMPANY (US) | 1995-08-30 | — | — | EP | disclosed |
| WO-1994011361-A1 | PYRAN-2-ONES AND 5,6-DIHYDROPYRAN-2-ONES USEFUL FOR TREATING HIV AND OTHER RETROVIRUSES | THE UPJOHN COMPANY (US) | 1994-05-26 | — | — | WO | disclosed |