Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2B | P41595 | 1/20 | 0.46 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.44 |
| ▸ | PARP1 | P09874 | 3/20 | 0.42 |
| ▸ | EIF4E | P06730 | 3/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.40 |
| ▸ | JAK2 | O60674 | 1/20 | 0.39 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.39 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.39 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | GRM5 | P41594 | 1/20 | 0.36 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.36 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30430147 | 0.87 | RAB9A (0.55) | EIF4EACHENPC1RAB9ASMN1; SMN2 | |
| SCHEMBL28203738 | 0.82 | GFER (0.38) | HTR2BEIF4EACHECYP2C9SCN9A | |
| SCHEMBL3180259 | 0.78 | HTR2B (0.50) | HTR2BBCAT2EIF4EACHENPC1 | |
| SCHEMBL2706854 | 0.77 | TGFBR1 (0.51) | HTR2BBCAT2PARP1EIF4EACHE | |
| SCHEMBL3177607 | 0.77 | HTR2B (0.49) | HTR2BBCAT2EIF4EACHENPC1 | |
| SCHEMBL3260631 | 0.77 | CHRM1 (0.52) | HTR2BBCAT2PARP1EIF4EACHE | |
| SCHEMBL6227934 | 0.76 | ALDH1A1 (0.44) | HTR2BACHENPC1RAB9ASMN1; SMN2 | |
| SCHEMBL30310815 | 0.76 | MPL (0.47) | NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL11177459 | 0.75 | HTR2B (0.44) | HTR2BBCAT2EIF4EACHENPC1 | |
| SCHEMBL7693823 | 0.75 | CTNNB1 (0.47) | HTR2BPARP1CYP2C9SCN9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107734969-A | Molecules having pesticidal utility, and intermediates, compositions and methods related thereto | 美国陶氏益农公司 | 2018-02-23 | — | — | CN | disclosed |
| EP-2334652-A1 | 1H-BENZ IMIDAZOLE-5-CARBOXAMIDES AS ANTI-INFLAMMATORY AGENTS | Boehringer Ingelheim International GmbH (DE) | 2011-06-22 | — | — | EP | disclosed |