SCHEMBL19681293

CCCCCCCCC[C@H]1O[C@@H](n2cc(C)c(N)nc2=O)CC1OP(=O)(S)OC[C@H]1O[C@@H](n2cc(C)c(=O)[nH]c2=O)CC1OP(=O)(S)OC[C@H]1O[C@@H](n2cc(C)c(=O)[nH]c2=O)CC1OP(=O)(S)OC[C@H]1O[C@@H](n2cc(C)c(=O)[nH]c2=O)CC1OP(=O)(S)OC[C@H]1O[C@@H](n2cnc3c(N)ncnc32)CC1OP(=O)(S)OC[C@H]1O[C@@H](n2cc(C)c(=O)[nH]c2=O)CC1OP(=O)(O)OC[C@H]1O[C@@H](n2cc(C)c(N)nc2=O)C[C@H]1OP(=O)(O)O

nearest known ligand 0.55

Predicted protein targets (top 4)

	gene	UniProt	supporting neighbours	confidence
▸	DTYMK	P23919	4/20	0.55

▸	TERT	O14746	2/20	0.53

▸	F2	P00734	2/20	0.43

▸	RNASEL	Q05823	1/20	0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL19677796	0.90	DTYMK (0.57)	DTYMKTERTF2RNASEL
SCHEMBL19677797	0.88	DTYMK (0.57)	DTYMKTERTF2
SCHEMBL23801880	0.87	DTYMK (0.54)	DTYMKTERTRNASEL
SCHEMBL24858894	0.86	TERT (0.52)	DTYMKTERTF2
SCHEMBL18472104	0.86	DTYMK (0.57)	DTYMKTERTF2RNASEL
SCHEMBL16221581	0.86	DTYMK (0.53)	DTYMKTERTF2
SCHEMBL20024801	0.86	DTYMK (0.54)	DTYMKTERTF2
SCHEMBL17775306	0.86	DTYMK (0.54)	DTYMKTERTF2
SCHEMBL18159196	0.86	DTYMK (0.54)	DTYMKTERTF2
SCHEMBL18472073	0.86	DTYMK (0.54)	DTYMKTERTF2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-20170349897-A1	COMPOSITIONS FOR MODULATING C9ORF72 EXPRESSION	IONIS PHARMACEUTICALS, INC. (US)	2017-12-07	—	—	US	disclosed