Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 3/20 | 0.42 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | NPY5R | Q15761 | 6/20 | 0.40 |
| ▸ | NPY1R | P25929 | 5/20 | 0.40 |
| ▸ | NPY4R | P50391 | 5/20 | 0.40 |
| ▸ | NPY2R | P49146 | 3/20 | 0.40 |
| ▸ | C3AR1 | Q16581 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | REN | P00797 | 1/20 | 0.39 |
| ▸ | CTSD | P07339 | 1/20 | 0.39 |
| ▸ | BACE1 | P56817 | 1/20 | 0.39 |
| ▸ | SIRT1 | Q96EB6 | 2/20 | 0.38 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23189264 | 1.00 | ITGB3 (0.42) | ITGB3ITGA2BSMN1; SMN2NPC1RAB9A | |
| SCHEMBL24539700 | 0.88 | C3AR1 (0.42) | SMN1; SMN2C3AR1SIRT1SIRT2ADAM10 | |
| SCHEMBL24701258 | 0.88 | C3AR1 (0.42) | SMN1; SMN2C3AR1SIRT1SIRT2ADAM10 | |
| SCHEMBL20043710 | 0.88 | SIRT2 (0.46) | ITGB3ITGA2BSIRT1SIRT2 | |
| SCHEMBL24728476 | 0.87 | C3AR1 (0.40) | NPY5RNPY1RNPY4RNPY2RC3AR1 | |
| SCHEMBL17683439 | 0.87 | SIRT2 (0.45) | ITGB3ITGA2BSIRT1SIRT2 | |
| SCHEMBL23347054 | 0.87 | SIRT2 (0.45) | ITGB3ITGA2BSIRT1SIRT2 | |
| SCHEMBL12634420 | 0.87 | TAAR1 (0.41) | NPY5RNPY1RNPY4RNPY2RSIRT1 | |
| SCHEMBL18738463 | 0.86 | SMN1; SMN2 (0.45) | SMN1; SMN2NPC1RAB9APTPN1HPGD | |
| SCHEMBL26170358 | 0.86 | MAPT (0.47) | C3AR1SIRT1ALDH1A1MAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023116911-A1 | ANTI-FRα ANTIBODY, AND ANTIBODY-DRUG CONJUGATE AND USE THEREOF | 百奥泰生物制药股份有限公司 | 2023-06-29 | — | — | WO | disclosed |
| WO-2023061457-A1 | ANTIBODY-DRUG CONJUGATE AND APPLICATION THEREOF | 百奥泰生物制药股份有限公司 | 2023-04-20 | — | — | WO | disclosed |
| WO-2022253284-A1 | DRUG CONJUGATE AND USE THEREOF | 百奥泰生物制药股份有限公司 | 2022-12-08 | — | — | WO | disclosed |
| US-20210100912-A1 | ANTIBODY-DRUG CONJUGATE HAVING ACIDIC SELF-STABILIZATION JUNCTION | SYSTIMMUNE, INC. | 2021-04-08 | — | — | US | disclosed |
| WO-2018127699-A1 | COMPOUNDS FOR TREATING CANCER | Bicyclerd Limited (GB) | 2018-07-12 | — | — | WO | disclosed |
| WO-2017210288-A1 | ANTIBODY DRUG CONJUGATES HAVING DERIVATIVES OF AMATOXIN AS THE DRUG | SORRENTO THERAPEUTICS, INC. (US) | 2017-12-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210100912-A1 | ANTIBODY-DRUG CONJUGATE HAVING ACIDIC SELF-STABILIZATION JUNCTION | CD44, EPCAM, FCGR1A | ITGB3 1246/4885ITGA2B 845/4885SMN1; SMN2 2445/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.