Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.47 |
| ▸ | ANPEP | P15144 | 1/20 | 0.45 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | C3AR1 | Q16581 | 1/20 | 0.41 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.41 |
| ▸ | ADAM10 | O14672 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | MMP9 | P14780 | 1/20 | 0.41 |
| ▸ | MMP12 | P39900 | 1/20 | 0.41 |
| ▸ | MMP14 | P50281 | 1/20 | 0.41 |
| ▸ | ADAM8 | P78325 | 1/20 | 0.41 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.41 |
| ▸ | KLK7 | P49862 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19681568 | 0.86 | ITGB3 (0.42) | MAPTL3MBTL1ALDH1A1C3AR1SIRT1 | |
| SCHEMBL23189264 | 0.86 | ITGB3 (0.42) | MAPTL3MBTL1ALDH1A1C3AR1SIRT1 | |
| SCHEMBL23962289 | 0.85 | MAPT (0.47) | MAPTANPEPPRMT1HTTL3MBTL1 | |
| SCHEMBL20043710 | 0.85 | SIRT2 (0.46) | SIRT1 | |
| SCHEMBL17683439 | 0.84 | SIRT2 (0.45) | SIRT1 | |
| SCHEMBL23347054 | 0.84 | SIRT2 (0.45) | SIRT1 | |
| SCHEMBL24329149 | 0.83 | SIRT2 (0.41) | C3AR1SIRT1ADAM10MMP2MMP9 | |
| SCHEMBL21205432 | 0.82 | SIRT2 (0.48) | SIRT1 | |
| SCHEMBL26170667 | 0.81 | CPB1 (0.47) | SIRT1 | |
| SCHEMBL24809330 | 0.80 | SIRT2 (0.46) | SIRT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023097407-A1 | MODIFIED AMATOXINS AND USES THEREOF | THE UNIVERSITY OF BRITISH COLUMBIA (CA) | 2023-06-08 | — | — | WO | disclosed |