Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.46 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | TGM2 | P21980 | 6/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | LTA4H | P09960 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27988246 | 0.94 | ZDHHC20 (0.50) | ZDHHC20ZDHHC2ALDH1A1TSHRMAPK1 | |
| SCHEMBL14820451 | 0.94 | ZDHHC20 (0.50) | ZDHHC20ZDHHC2ALDH1A1TSHRMAPK1 | |
| SCHEMBL28262483 | 0.91 | ZDHHC20 (0.50) | ZDHHC20ZDHHC2ALDH1A1TSHRMAPK1 | |
| SCHEMBL28261348 | 0.88 | ZDHHC20 (0.50) | ZDHHC20ZDHHC2ALDH1A1TSHRMAPK1 | |
| SCHEMBL17858061 | 0.85 | ZDHHC20 (0.52) | ZDHHC20ZDHHC2ALDH1A1TSHRMAPK1 | |
| SCHEMBL12301856 | 0.83 | ZDHHC20 (0.52) | ZDHHC20ZDHHC2ALDH1A1TSHRMAPK1 | |
| SCHEMBL866404 | 0.82 | ZDHHC20 (0.51) | ZDHHC20ZDHHC2ALDH1A1TSHRMAPK1 | |
| SCHEMBL6341877 | 0.81 | ZDHHC20 (0.61) | ZDHHC20ZDHHC2ALDH1A1TSHRMAPK1 | |
| SCHEMBL18331600 | 0.80 | ZDHHC20 (0.59) | ZDHHC20ZDHHC2ALDH1A1TSHRMAPK1 | |
| SCHEMBL177994 | 0.80 | ZDHHC20 (0.58) | ZDHHC20ZDHHC2ALDH1A1TSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170349543-A1 | CATIONIC SULFONAMIDE AMINO LIPIDS AND AMPHIPHILIC ZWITTERIONIC AMINO LIPIDS | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2017-12-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170349543-A1 | CATIONIC SULFONAMIDE AMINO LIPIDS AND AMPHIPHILIC ZWITTERIONIC AMINO LIPIDS | ABHD16A, AARS1, CFTR | ZDHHC20 676/4885ZDHHC2 573/4885ALDH1A1 4503/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.