Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 2/20 | 0.40 |
| ▸ | FAAH | O00519 | 6/20 | 0.37 |
| ▸ | CASP2 | P42575 | 1/20 | 0.36 |
| ▸ | NAAA | Q02083 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | TLR2 | O60603 | 1/20 | 0.33 |
| ▸ | KDM5A | P29375 | 1/20 | 0.33 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.33 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19681584 | 0.89 | DNM1 (0.39) | DNM1FAAHCASP2NAAAL3MBTL1 | |
| SCHEMBL25681831 | 0.84 | FAAH (0.36) | DNM1FAAHCASP2NAAAL3MBTL1 | |
| SCHEMBL19681640 | 0.84 | DNM1 (0.35) | DNM1CASP2NAAAEPHX2TLR2 | |
| SCHEMBL25963592 | 0.83 | DNM1 (0.48) | DNM1FAAHCASP2NAAAL3MBTL1 | |
| SCHEMBL19681639 | 0.83 | FAAH (0.47) | DNM1FAAHCASP2NAAAL3MBTL1 | |
| SCHEMBL25964558 | 0.82 | DNM1 (0.45) | DNM1FAAHCASP2NAAAL3MBTL1 | |
| SCHEMBL25963506 | 0.81 | DNM1 (0.47) | DNM1FAAHCASP2NAAAL3MBTL1 | |
| SCHEMBL25963572 | 0.81 | DNM1 (0.47) | DNM1FAAHCASP2NAAAL3MBTL1 | |
| SCHEMBL25963546 | 0.81 | DNM1 (0.47) | DNM1FAAHCASP2NAAAL3MBTL1 | |
| SCHEMBL25963457 | 0.81 | DNM1 (0.50) | DNM1FAAHCASP2NAAAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170349543-A1 | CATIONIC SULFONAMIDE AMINO LIPIDS AND AMPHIPHILIC ZWITTERIONIC AMINO LIPIDS | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2017-12-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170349543-A1 | CATIONIC SULFONAMIDE AMINO LIPIDS AND AMPHIPHILIC ZWITTERIONIC AMINO LIPIDS | ABHD16A, AARS1, CFTR | DNM1 700/4885FAAH 935/4885CASP2 2627/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.