Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | PTGIR | P43119 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | MLYCD | O95822 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 5/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11507985 | 0.90 | ALDH1A1 (0.54) | MAPTALDH1A1PTGIRL3MBTL1HPGD | |
| SCHEMBL22100714 | 0.90 | L3MBTL1 (0.43) | MAPTALDH1A1PTGIRL3MBTL1HPGD | |
| SCHEMBL44533 | 0.84 | — | — | |
| SCHEMBL15933122 | 0.84 | PTGIR (0.43) | MAPTALDH1A1PTGIRL3MBTL1HPGD | |
| Hydrochloric Acid SCHEMBL2866389 | 0.82 | MAPT (0.50) | MAPTALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL83853 | 0.82 | ACHE (0.57) | MAPTALDH1A1PTGIRL3MBTL1HPGD | |
| SCHEMBL11121834 | 0.82 | ACHE (0.57) | MAPTALDH1A1PTGIRL3MBTL1HPGD | |
| SCHEMBL12245875 | 0.82 | ACHE (0.57) | MAPTALDH1A1PTGIRL3MBTL1HPGD | |
| SCHEMBL6975747 | 0.81 | TSHR (0.59) | MAPTALDH1A1PTGIRHPGDMEN1 | |
| SCHEMBL19681866 | 0.80 | L3MBTL1 (0.42) | MAPTALDH1A1PTGIRL3MBTL1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3901162-A1 | GLUCOCORTICOID RECEPTOR AGONIST AND IMMUNOCONJUGATES THEREOF | AbbVie Inc. (US) | 2021-10-27 | — | — | EP | disclosed |
| WO-2017207776-A1 | SYSTEM FOR DISPENSING A COSMETIC PRODUCT | L'OREAL (FR) | 2017-12-07 | — | — | WO | disclosed |