Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 5/20 | 0.39 |
| ▸ | SIRT1 | Q96EB6 | 5/20 | 0.39 |
| ▸ | SIRT3 | Q9NTG7 | 5/20 | 0.39 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.39 |
| ▸ | PLAU | P00749 | 1/20 | 0.37 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.37 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.37 |
| ▸ | KDM4A | O75164 | 1/20 | 0.37 |
| ▸ | ELANE | P08246 | 4/20 | 0.37 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.37 |
| ▸ | SIRT7 | Q9NRC8 | 3/20 | 0.37 |
| ▸ | SIRT6 | Q8N6T7 | 2/20 | 0.37 |
| ▸ | OXTR | P30559 | 1/20 | 0.37 |
| ▸ | NNMT | P40261 | 2/20 | 0.36 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12518412 | 0.84 | ITGB3 (0.44) | SIRT2SIRT1SIRT3ITGB3ITGA2B | |
| SCHEMBL19682189 | 0.77 | KLKB1 (0.45) | CACNA1BPLAUITGB3ITGA2BKLKB1 | |
| SCHEMBL29666716 | 0.77 | PIN1 (0.46) | CACNA1BPLAUITGB3KDM4APIN1 | |
| SCHEMBL29569256 | 0.75 | ITGB3 (0.44) | SIRT2SIRT1SIRT3CACNA1BITGB3 | |
| SCHEMBL29569103 | 0.75 | ITGB3 (0.44) | SIRT2SIRT1SIRT3CACNA1BITGB3 | |
| SCHEMBL23391095 | 0.74 | OXTR (0.43) | SIRT2SIRT1SIRT3ITGB3ITGA2B | |
| SCHEMBL19605445 | 0.73 | ITGB3 (0.55) | ITGB3ITGA2B | |
| SCHEMBL24975502 | 0.72 | PIN1 (0.49) | ITGB3ITGA2BPIN1 | |
| SCHEMBL20982086 | 0.72 | ITGB3 (0.51) | CACNA1BITGB3ITGA2B | |
| SCHEMBL23999304 | 0.72 | ITGB3 (0.51) | CACNA1BITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017210246-A2 | PENICILLAMINE CONJUGATES AND PARTICLES AND FORMULATIONS THEREOF | TARVEDA THERAPEUTICS, INC. (US) | 2017-12-07 | — | — | WO | disclosed |