Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LDHA | P00338 | 2/20 | 0.44 |
| ▸ | CYP46A1 | Q9Y6A2 | 7/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26081233 | 0.87 | KDM4E (0.45) | ALDH1A1KDM4ETDP1CYP3A4LMNA | |
| SCHEMBL30315919 | 0.86 | BCAT2 (0.46) | CYP46A1ALDH1A1KDM4ECLK4MEN1 | |
| SCHEMBL8577575 | 0.84 | ALDH1A1 (0.44) | CYP46A1ATMALDH1A1MEN1KMT2A | |
| SCHEMBL1972138 | 0.84 | GAA (0.47) | ALDH1A1KDM4EKMT2AHPGD | |
| SCHEMBL1968017 | 0.84 | KDM4E (0.44) | CYP46A1ALDH1A1KDM4ECYP1A2CYP3A4 | |
| SCHEMBL6490977 | 0.84 | CSNK2A2 (0.49) | ALDH1A1KDM4ETDP1CYP1A2CYP3A4 | |
| SCHEMBL1970118 | 0.82 | KMO (0.50) | ALDH1A1ALOX15CYP1A2CYP3A4TSHR | |
| SCHEMBL1967237 | 0.82 | KMO (0.50) | ALDH1A1CYP1A2CYP3A4TSHRCLK4 | |
| SCHEMBL1970072 | 0.82 | KMO (0.50) | LDHACYP1A2CYP3A4CYP2C19MEN1 | |
| SCHEMBL13531230 | 0.82 | MAPT (0.50) | CYP46A1ATMALDH1A1TDP1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102164896-A | Phenethylamide derivatives and their heterocyclic analogues | ACTELION PHARMACEUTICALS LTD | 2011-08-24 | — | — | CN | claimed |
| WO-2010044054-A1 | PHENETHYLAMIDE DERIVATIVES AND THEIR HETEROCYCLIC ANALOGUES | ACTELION PHARMACEUTICALS LTD (CH) | 2010-04-22 | — | — | WO | claimed |
| CN-1025556-C | Solvent extraction process | ICI PLC (GB) | 1994-08-03 | — | — | CN | claimed |
| EP-0332314-B1 | SOLVENT EXTRACTION PROCESS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-12-23 | — | — | EP | claimed |
| US-4961856-A | CONTACTING AQUEOUS SOLUTION CONTAINING PALLADIUM WITH SOLUTION OF SUBSTITUTED HETEROCYCLIC RING COMPOUND | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1990-10-09 | — | — | US | claimed |
| CN-1035851-A | SOLVENT EXTRACTION PROCESS | ICI PLC (GB) | 1989-09-27 | — | — | CN | claimed |
| EP-0332314-A2 | Solvent extraction process | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1989-09-13 | — | — | EP | claimed |
| EP-3442965-B1 | NOVEL N-[(HETEROARYLOXY)PROPANYL]HETEROARYL CARBOXAMIDES | BOEHRINGER INGELHEIM INT (DE) | 2021-05-26 | — | — | EP | disclosed |
| EP-3442965-B1 | NOVEL N-[(HETEROARYLOXY)PROPANYL]HETEROARYL CARBOXAMIDES | BOEHRINGER INGELHEIM INT (DE) | 2021-05-26 | — | — | EP | disclosed |
| US-10738031-B2 | N-[(heteroaryloxy)propanyl]heteroaryl carboxamides as antagonists of orexin subtype 1 receptor activity | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2020-08-11 | — | — | US | disclosed |
| US-10738031-B2 | N-[(heteroaryloxy)propanyl]heteroaryl carboxamides as antagonists of orexin subtype 1 receptor activity | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2020-08-11 | — | — | US | disclosed |
| EP-3442964-B1 | NOVEL N-[(PYRIMIDINYLAMINO)PROPANYL]-AND N [(PYRAZINYLAMINO)PROPANYL]ARYLCARBOXAMIDES | BOEHRINGER INGELHEIM INT (DE) | 2020-05-06 | — | — | EP | disclosed |
| EP-3442964-B1 | NOVEL N-[(PYRIMIDINYLAMINO)PROPANYL]-AND N [(PYRAZINYLAMINO)PROPANYL]ARYLCARBOXAMIDES | BOEHRINGER INGELHEIM INT (DE) | 2020-05-06 | — | — | EP | disclosed |
| US-4961856-A | CONTACTING AQUEOUS SOLUTION CONTAINING PALLADIUM WITH SOLUTION OF SUBSTITUTED HETEROCYCLIC RING COMPOUND | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1990-10-09 | — | — | US | disclosed |
| CN-1035851-A | SOLVENT EXTRACTION PROCESS | ICI PLC (GB) | 1989-09-27 | — | — | CN | disclosed |
| EP-0332314-A2 | Solvent extraction process | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1989-09-13 | — | — | EP | disclosed |
| EP-0112617-B1 | PROCESS FOR THE EXTRACTION OF METAL VALUES AND NOVEL METAL EXTRACTANTS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1986-12-30 | — | — | EP | disclosed |
| US-4581220-A | CURED RESIDUE OF ZIRCONIUM SOLUTION | IMPERIAL CHEMICAL INDUSTRIES, PLC (GB) | 1986-04-08 | — | — | US | disclosed |
| US-4576815-A | Process for the extraction of metal values and novel metal extractants | IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) | 1986-03-18 | — | — | US | disclosed |
| EP-0112617-A1 | Process for the extraction of metal values and novel metal extractants | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1984-07-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10738031-B2 | N-[(heteroaryloxy)propanyl]heteroaryl carboxamides as antagonists of orexin subtype 1 receptor activity | HCRTR2, HCRTR1, CNR1 | LDHA 2592/4885CYP46A1 419/4885ATM 4856/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.