Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.57 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.57 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.49 |
| ▸ | EPHX2 | P34913 | 5/20 | 0.48 |
| ▸ | NR1H4 | Q96RI1 | 5/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.46 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.46 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.45 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.45 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.45 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10165179 | 0.87 | NAMPT (0.56) | KMT2AHDAC1HDAC6RAB9AMAPT | |
| SCHEMBL6945571 | 0.87 | HTT (0.50) | KMT2AHDAC6RAB9AMAPTEPHX2 | |
| SCHEMBL28283361 | 0.84 | KMT2A (0.57) | KMT2AHDAC1HDAC6RAB9AALDH1A1 | |
| SCHEMBL15259134 | 0.83 | L3MBTL1 (0.56) | KMT2AHDAC1HDAC6RAB9AALDH1A1 | |
| SCHEMBL23409688 | 0.83 | HTT (0.47) | KMT2AHDAC6RAB9AALDH1A1MAPT | |
| SCHEMBL18954397 | 0.83 | EPHX2 (0.50) | KMT2AHDAC6RAB9APOLBHDAC3 | |
| SCHEMBL22837952 | 0.83 | EPHX2 (0.47) | KMT2AHDAC6RAB9AHDAC3EPHX2 | |
| SCHEMBL12252575 | 0.83 | KMT2A (0.68) | KMT2AHDAC1HDAC6RAB9AALDH1A1 | |
| SCHEMBL5357067 | 0.83 | KMT2A (0.68) | KMT2AHDAC1HDAC6RAB9AALDH1A1 | |
| SCHEMBL34481 | 0.82 | CA1 (0.53) | HDAC6MAPTEPHX2NR1H4GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10954316-B2 | Method for cleaving amide bonds | Galderma Holding SA (CH) | 2021-03-23 | — | — | US | disclosed |
| EP-2582709-B1 | AZOLOPYRIDIN-3-ONE DERIVATIVES AS INHIBITORS OF LIPASES AND PHOSPHOLIPASES | SANOFI SA (FR) | 2018-01-24 | — | — | EP | disclosed |
| WO-2017207564-A1 | METHOD FOR CLEAVING AMIDE BONDS | GALDERMA S.A. (CH) | 2017-12-07 | — | — | WO | disclosed |