Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | EPHX2 | P34913 | 6/20 | 0.48 |
| ▸ | NR1H4 | Q96RI1 | 4/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
| ▸ | NAMPT | P43490 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19682558 | 0.87 | KMT2A (0.60) | EPHX2NR1H4KMT2AMEN1RAB9A | |
| SCHEMBL10165179 | 0.87 | NAMPT (0.56) | EPHX2NR1H4KMT2AMEN1RAB9A | |
| SCHEMBL23409688 | 0.83 | HTT (0.47) | HTTEPHX2NR1H4SMN1; SMN2KMT2A | |
| SCHEMBL22837952 | 0.83 | EPHX2 (0.47) | EPHX2NR1H4KMT2AMEN1RAB9A | |
| SCHEMBL18954397 | 0.83 | EPHX2 (0.50) | EPHX2NR1H4KMT2AMEN1RAB9A | |
| SCHEMBL34481 | 0.82 | CA1 (0.53) | EPHX2NR1H4SMN1; SMN2LMNAHDAC6 | |
| SCHEMBL13884422 | 0.81 | CA1 (0.49) | HTTKMT2AMEN1LMNANAMPT | |
| SCHEMBL6451649 | 0.81 | CA1 (0.48) | EPHX2NR1H4SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL7428120 | 0.81 | HDAC1 (0.56) | SMN1; SMN2KMT2AMEN1LMNANAMPT | |
| SCHEMBL7322209 | 0.80 | HTT (0.73) | HTTSMN1; SMN2KMT2AMEN1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0944582-B1 | KETOBENZAMIDES AS CALPAIN INHIBITORS | ABBOTT GMBH & CO KG (DE) | 2003-07-02 | — | — | EP | disclosed |