Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.66 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.63 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.63 |
| ▸ | HDAC1 | Q13547 | 8/20 | 0.62 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 1/20 | 0.60 |
| ▸ | RAB9A | P51151 | 1/20 | 0.60 |
| ▸ | HDAC2 | Q92769 | 7/20 | 0.53 |
| ▸ | HDAC3 | O15379 | 6/20 | 0.53 |
| ▸ | ACACB | O00763 | 1/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 6/20 | 0.49 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.49 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.49 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.48 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.48 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.48 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23471131 | 0.83 | KMT2A (0.62) | KMT2AHDAC1HDAC6ALDH1A1POLB | |
| SCHEMBL12133623 | 0.82 | KMT2A (0.76) | KMT2AHDAC1HDAC6ALDH1A1POLB | |
| SCHEMBL19634692 | 0.82 | KMT2A (0.57) | KMT2AEPHX2NR1H4HDAC1HDAC6 | |
| SCHEMBL22927824 | 0.81 | EPHX2 (0.58) | KMT2AEPHX2NR1H4HDAC1HDAC6 | |
| SCHEMBL19634440 | 0.81 | EPHX2 (0.58) | KMT2AEPHX2NR1H4HDAC1HDAC6 | |
| SCHEMBL21015472 | 0.81 | EPHX2 (0.67) | KMT2AEPHX2NR1H4HDAC1HDAC6 | |
| SCHEMBL5987974 | 0.81 | KMT2A (0.75) | KMT2AEPHX2NR1H4HDAC1HDAC6 | |
| SCHEMBL19634702 | 0.80 | HDAC1 (0.52) | KMT2AEPHX2NR1H4HDAC1HDAC6 | |
| SCHEMBL19634448 | 0.80 | KMT2A (0.58) | KMT2AEPHX2NR1H4HDAC1HDAC6 | |
| SCHEMBL11618011 | 0.80 | EPHX2 (0.56) | KMT2AEPHX2NR1H4ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10954316-B2 | Method for cleaving amide bonds | Galderma Holding SA (CH) | 2021-03-23 | — | — | US | disclosed |
| US-10954316-B2 | Method for cleaving amide bonds | Galderma Holding SA (CH) | 2021-03-23 | — | — | US | disclosed |
| US-20200172473-A1 | DUAL MODULATORS OF FARNESOID X RECEPTOR AND SOLUBLE EPOXIDE HYDROLASE | JOHANN WOLFGANG GOETHE-UNIVERSITAET FRANKFURT AM MAIN (DE) | 2020-06-04 | — | — | US | disclosed |
| WO-2017207564-A1 | METHOD FOR CLEAVING AMIDE BONDS | GALDERMA S.A. (CH) | 2017-12-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200172473-A1 | DUAL MODULATORS OF FARNESOID X RECEPTOR AND SOLUBLE EPOXIDE HYDROLASE | NR1H4, NR1H3, NR1H2 | KMT2A 3284/4885EPHX2 6/4885NR1H4 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.