SCHEMBL19682929

SCHEMBL19682929

Cc1ccc(F)c2c1OCCC2=O

nearest known ligand 0.42

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
CHRM2 P08172 3/20 0.42
CHRM1 P11229 3/20 0.42
RRM1 P23921 3/20 0.42
RRM2B Q7LG56 3/20 0.42
LMNA P02545 1/20 0.42
MAPT P10636 1/20 0.42
MAOA P21397 2/20 0.38
MAOB P27338 2/20 0.38
TERT O14746 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3267365 0.89 LMNA (0.42) CHRM2CHRM1RRM1RRM2BLMNA
SCHEMBL3272238 0.88 LMNA (0.46) CHRM2CHRM1RRM1RRM2BLMNA
SCHEMBL8316043 0.85 LMNA (0.50) CHRM2CHRM1RRM1RRM2BLMNA
SCHEMBL12565316 0.79 LMNA (0.42) CHRM2CHRM1RRM1RRM2BLMNA
SCHEMBL91638 0.79 LMNA (0.42) CHRM2CHRM1RRM1RRM2BLMNA
SCHEMBL9404823 0.79 LMNA (0.65) CHRM2CHRM1RRM1RRM2BLMNA
SCHEMBL21752292 0.76 LMNA (0.39) CHRM2CHRM1RRM1RRM2BLMNA
SCHEMBL15344152 0.75 LMNA (0.38) CHRM2CHRM1RRM1RRM2BLMNA
SCHEMBL19682926 0.74 CHRM2 (0.42) CHRM2CHRM1RRM1RRM2BLMNA
SCHEMBL13541001 0.72 MAOA (0.53) LMNAMAPTMAOAMAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2017209155-A1 SULFONAMIDE COMPOUND OR SALT THEREOF 大鵬薬品工業株式会社 2017-12-07 WO disclosed