Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | MAOB | P27338 | 3/20 | 0.42 |
| ▸ | MAOA | P21397 | 2/20 | 0.42 |
| ▸ | TOP2A | P11388 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | NQO1 | P15559 | 1/20 | 0.32 |
| ▸ | POR | P16435 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.32 |
| ▸ | RRM1 | P23921 | 2/20 | 0.32 |
| ▸ | RRM2B | Q7LG56 | 2/20 | 0.32 |
| ▸ | BRD4 | O60885 | 2/20 | 0.31 |
| ▸ | NSD2 | O96028 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9404823 | 0.89 | LMNA (0.65) | LMNAMAPTMAOBMAOATOP2A | |
| SCHEMBL3272238 | 0.87 | LMNA (0.46) | LMNAMAPTMAOBMAOATOP2A | |
| SCHEMBL91638 | 0.85 | LMNA (0.42) | LMNAMAPTMAOBMAOACHRM2 | |
| SCHEMBL13541001 | 0.85 | MAOA (0.53) | LMNAMAPTMAOBMAOATOP2A | |
| SCHEMBL4654915 | 0.85 | LMNA (0.45) | LMNAMAPTMAOBMAOATOP2A | |
| SCHEMBL19682929 | 0.85 | CHRM2 (0.42) | LMNAMAPTMAOBMAOACHRM2 | |
| SCHEMBL19297124 | 0.83 | MAPT (0.43) | LMNAMAPTMAOBMAOATOP2A | |
| SCHEMBL9221299 | 0.83 | LMNA (0.43) | LMNAMAPTMAOBMAOATOP2A | |
| SCHEMBL7657640 | 0.78 | ALDH1A1 (0.39) | LMNAMAPTMAOBMAOAALDH1A1 | |
| SCHEMBL10079888 | 0.77 | LMNA (0.51) | LMNAMAPTALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230286963-A1 | CHROMENONE COMPOUNDS FOR CONTROLLING INVERTEBRATE PESTS | FMC CORPORATION | 2023-09-14 | — | — | US | disclosed |
| EP-0946540-A1 | SUBSTITUTED BENZOTHIOPYRANES SALTS AND THEIR USE AS HERBICIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1999-10-06 | — | — | EP | disclosed |
| US-5952266-A | HERBICIDES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1999-09-14 | — | — | US | disclosed |
| EP-0922032-A1 | HERBICIDAL PYRIDINYL AND PYRAZOLYLPHENYL KETONES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1999-06-16 | — | — | EP | disclosed |
| CN-1189161-A | Herbicidal ketals and spirocycles | DU PONT (US) | 1998-07-29 | — | — | CN | disclosed |
| WO-1998028291-A1 | SUBSTITUTED BENZOTHIOPYRANES SALTS AND THEIR USE AS HERBICIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1998-07-02 | — | — | WO | disclosed |
| EP-0836600-A1 | HERBICIDAL KETALS AND SPIROCYCLES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1998-04-22 | — | — | EP | disclosed |
| WO-1997046530-A1 | HERBICIDAL PYRIDINYL AND PYRAZOLYLPHENYL KETONES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1997-12-11 | — | — | WO | disclosed |
| WO-1997001550-A1 | HERBICIDAL KETALS AND SPIROCYCLES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1997-01-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230286963-A1 | CHROMENONE COMPOUNDS FOR CONTROLLING INVERTEBRATE PESTS | CHRM1, CHRM2, CHRM3 | LMNA 1643/4885MAPT 4830/4885MAOB 786/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.