Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP2 | P42575 | 1/20 | 0.47 |
| ▸ | EPHX1 | P07099 | 6/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | NAAA | Q02083 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 2/20 | 0.42 |
| ▸ | MMP2 | P08253 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | FAAH | O00519 | 3/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26151157 | 0.88 | MCL1 (0.45) | CASP2EPHX1MEN1KMT2ATP53 | |
| SCHEMBL22433524 | 0.85 | KMT2A (0.42) | CASP2MEN1KMT2ATP53SMN1; SMN2 | |
| SCHEMBL7325345 | 0.83 | SMN1; SMN2 (0.59) | CASP2EPHX1MEN1KMT2ANAAA | |
| SCHEMBL19957980 | 0.82 | PAOX (0.52) | CASP2EPHX1MEN1KMT2ANAAA | |
| SCHEMBL19957918 | 0.82 | PAOX (0.52) | CASP2EPHX1MEN1KMT2ANAAA | |
| SCHEMBL16588651 | 0.82 | ALDH1A1 (0.40) | MEN1KMT2ANAAATP53SMN1; SMN2 | |
| SCHEMBL5907669 | 0.82 | CASP2 (0.48) | CASP2EPHX1MEN1KMT2ANAAA | |
| SCHEMBL19682981 | 0.80 | CASP2 (0.44) | CASP2EPHX1MEN1KMT2ANAAA | |
| SCHEMBL25918071 | 0.80 | CASP2 (0.44) | CASP2MEN1KMT2ANAAATP53 | |
| SCHEMBL28241142 | 0.80 | CASP2 (0.47) | CASP2EPHX1MEN1KMT2ANAAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2672998-B1 | INJECTABLE THERMORESPONSIVE POLYELECTROLYTES | UNIV NORTHWESTERN (US) | 2018-06-27 | — | — | EP | disclosed |