Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.52 |
| ▸ | MAOB | P27338 | 2/20 | 0.50 |
| ▸ | TNNC1 | P63316 | 5/20 | 0.46 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.46 |
| ▸ | SGPL1 | O95470 | 1/20 | 0.46 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.46 |
| ▸ | GPR183 | P32249 | 1/20 | 0.46 |
| ▸ | CERS2 | Q96G23 | 1/20 | 0.46 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.46 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.46 |
| ▸ | GFER | P55789 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18387848 | 0.87 | MAOB (0.47) | HTR2AMAOBTNNC1S1PR1SGPL1 | |
| SCHEMBL109256 | 0.82 | HTR2A (0.72) | HTR2AMAOBTNNC1S1PR1SGPL1 | |
| SCHEMBL13526966 | 0.81 | MAOB (0.57) | HTR2AMAOBTNNC1S1PR1SGPL1 | |
| Undecane SCHEMBL22346217 | 0.81 | HTR2A (0.76) | HTR2AMAOBTNNC1S1PR1SGPL1 | |
| SCHEMBL23754735 | 0.81 | HTR2A (0.76) | HTR2AMAOBTNNC1S1PR1SGPL1 | |
| SCHEMBL23754742 | 0.81 | HTR2A (0.76) | HTR2AMAOBTNNC1S1PR1SGPL1 | |
| Pentadecane SCHEMBL22346204 | 0.81 | HTR2A (0.76) | HTR2AMAOBTNNC1S1PR1SGPL1 | |
| SCHEMBL22346501 | 0.81 | HTR2A (0.76) | HTR2AMAOBTNNC1S1PR1SGPL1 | |
| SCHEMBL22346194 | 0.81 | HTR2A (0.76) | HTR2AMAOBTNNC1S1PR1SGPL1 | |
| SCHEMBL22346250 | 0.81 | HTR2A (0.76) | HTR2AMAOBTNNC1S1PR1SGPL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170349621-A1 | TRIAZOLE COMPOUNDS AND METHODS OF MAKING AND USING THE SAME | BioVersys AG (CH) | 2017-12-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170349621-A1 | TRIAZOLE COMPOUNDS AND METHODS OF MAKING AND USING THE SAME | PROKR1, ARG1, ARG2 | HTR2A 2234/4885MAOB 1841/4885TNNC1 1319/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.