Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 4/20 | 0.73 |
| ▸ | LMNA | P02545 | 5/20 | 0.70 |
| ▸ | TSHR | P16473 | 2/20 | 0.70 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.68 |
| ▸ | MAPT | P10636 | 3/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.68 |
| ▸ | MEN1 | O00255 | 1/20 | 0.68 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.68 |
| ▸ | HTT | P42858 | 1/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.68 |
| ▸ | CNR2 | P34972 | 5/20 | 0.62 |
| ▸ | TP53 | P04637 | 1/20 | 0.62 |
| ▸ | CNR1 | P21554 | 4/20 | 0.61 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.58 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 2/20 | 0.56 |
| ▸ | RAB9A | P51151 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19668631 | 0.84 | ENPP2 (1.00) | ENPP2LMNATSHRSMN1; SMN2MAPK1 | |
| SCHEMBL17124855 | 0.78 | LMNA (0.81) | ENPP2LMNATSHRSMN1; SMN2MAPT | |
| SCHEMBL19392300 | 0.77 | KMT2A (0.77) | LMNATSHRSMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL11180220 | 0.76 | PKM (0.61) | SMN1; SMN2ALDH1A1HTTKMT2ACNR2 | |
| SCHEMBL19668630 | 0.75 | ENPP2 (1.00) | ENPP2LMNATSHRSMN1; SMN2MAPK1 | |
| SCHEMBL18084766 | 0.75 | LMNA (0.78) | ENPP2LMNATSHRSMN1; SMN2MAPT | |
| SCHEMBL16903160 | 0.74 | LMNA (0.78) | ENPP2LMNATSHRSMN1; SMN2MAPT | |
| SCHEMBL21623277 | 0.74 | LMNA (0.84) | LMNATSHRSMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL18084732 | 0.74 | LMNA (0.82) | ENPP2LMNATSHRSMN1; SMN2MAPT | |
| SCHEMBL18377080 | 0.73 | CNR2 (0.67) | MAPTALDH1A1MAPK1HTTCNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017210527-A1 | AUTOTAXIN INHIBITORS | UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (US) | 2017-12-07 | — | — | WO | disclosed |