Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNK2 | Q07912 | 1/20 | 0.40 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.38 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.38 |
| ▸ | MEN1 | O00255 | 5/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | UBE2N | P61088 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.35 |
| ▸ | CHEK1 | O14757 | 3/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.34 |
| ▸ | AURKA | O14965 | 1/20 | 0.34 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.34 |
| ▸ | DDR2 | Q16832 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31672326 | 0.97 | TNK2 (0.40) | TNK2PLA2G2APLA2G4AKMT2AMEN1 | |
| SCHEMBL19683444 | 0.97 | TNK2 (0.40) | TNK2PLA2G2APLA2G4AKMT2AMEN1 | |
| SCHEMBL19683354 | 0.87 | PGR (0.37) | TNK2PLA2G2APLA2G4AKMT2AMEN1 | |
| SCHEMBL9925464 | 0.87 | TNK2 (0.49) | TNK2PLA2G2APLA2G4AKMT2AMEN1 | |
| SCHEMBL19683351 | 0.85 | PGR (0.35) | TNK2PLA2G2APLA2G4AKMT2AMEN1 | |
| SCHEMBL17190944 | 0.83 | PLA2G2A (0.40) | PLA2G2APLA2G4AKMT2AMEN1HSP90AA1 | |
| SCHEMBL18540439 | 0.83 | PTGS2 (0.48) | PLA2G2APLA2G4AKMT2AMEN1ALDH1A1 | |
| SCHEMBL17190943 | 0.82 | PLA2G2A (0.39) | PLA2G2APLA2G4AKMT2AMEN1HSP90AA1 | |
| SCHEMBL22414547 | 0.82 | TNK2 (0.38) | TNK2PLA2G2APLA2G4AKMT2AMEN1 | |
| SCHEMBL22414599 | 0.82 | TNK2 (0.38) | TNK2PLA2G2APLA2G4AKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017210072-A1 | ELECTROACTIVE COMPOUNDS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2017-12-07 | — | — | WO | disclosed |