SCHEMBL19683364

SCHEMBL19683364

c1ccc(N(c2ccc(-c3cc4ccccc4o3)cc2)c2ccc3cc(-c4cc5cc6cc7cc(-c8ccc9cc(N(c%10ccccc%10)c%10ccc(-c%11cc%12ccccc%12o%11)cc%10)ccc9c8)oc7cc6cc5o4)ccc3c2)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 3/20 0.47
ALOX5 P09917 1/20 0.45
CA1 P00915 1/20 0.42
CA2 P00918 1/20 0.42
CA9 Q16790 1/20 0.42
MAOA P21397 1/20 0.42
PTPRC P08575 1/20 0.41
PTPN1 P18031 1/20 0.41
RAB9A P51151 2/20 0.40
APP P05067 2/20 0.40
KDM4E B2RXH2 1/20 0.40
MEN1 O00255 1/20 0.40
NPC1 O15118 1/20 0.40
ALDH1A1 P00352 1/20 0.40
NFKB1 P19838 1/20 0.40
NPY1R P25929 1/20 0.40
NFKB2 Q00653 1/20 0.40
KMT2A Q03164 1/20 0.40
RELA Q04206 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31672328 1.00 MAOB (0.47) MAOBALOX5CA1CA2CA9
SCHEMBL19683537 0.92 MAOB (0.54) MAOBALOX5CA1CA2CA9
SCHEMBL20209465 0.92 ALOX5 (0.51) MAOBALOX5CA1CA2CA9
SCHEMBL20209470 0.88 MAOB (0.58) MAOBALOX5CA1CA2CA9
SCHEMBL26825203 0.87 MAOB (0.50) MAOBALOX5CA1CA2CA9
SCHEMBL19683533 0.87 MAOB (0.46) MAOBALOX5CA1CA2CA9
SCHEMBL26825171 0.86 MAOB (0.49) MAOBALOX5CA1CA2CA9
SCHEMBL26825049 0.86 MAOB (0.49) MAOBALOX5CA1CA2CA9
SCHEMBL26825185 0.86 MAOB (0.49) MAOBALOX5CA1CA2CA9
SCHEMBL26825129 0.86 MAOB (0.49) MAOBALOX5CA1CA2CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2017210072-A1 ELECTROACTIVE COMPOUNDS E. I. DU PONT DE NEMOURS AND COMPANY (US) 2017-12-07 WO disclosed