Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 4/20 | 0.50 |
| ▸ | MAOB | P27338 | 3/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.50 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.47 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 3/20 | 0.38 |
| ▸ | HTR2A | P28223 | 2/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.38 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.37 |
| ▸ | PIM1 | P11309 | 1/20 | 0.36 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.36 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1866520 | 0.87 | MTNR1A (0.48) | MAOAMAOBNFKB1MTNR1AMTNR1B | |
| SCHEMBL30423508 | 0.87 | MTNR1A (0.48) | MAOAMAOBNFKB1MTNR1AMTNR1B | |
| SCHEMBL19683503 | 0.85 | MAOA (0.41) | MAOAMAOBNFKB1MTNR1AMTNR1B | |
| SCHEMBL19683358 | 0.84 | MAOA (0.52) | MAOAMAOBNFKB1MTNR1AMTNR1B | |
| SCHEMBL31741279 | 0.82 | HPRT1 (0.50) | MAOAMAOBNFKB1MTNR1AMTNR1B | |
| SCHEMBL31158255 | 0.82 | MTNR1A (0.39) | MAOAMAOBNFKB1MTNR1AMTNR1B | |
| SCHEMBL31158256 | 0.81 | MTNR1A (0.38) | MAOAMAOBNFKB1MTNR1AMTNR1B | |
| SCHEMBL4429415 | 0.80 | PAX8 (0.48) | MAOAMAOBNFKB1CYP3A4KDM4E | |
| SCHEMBL30231603 | 0.80 | MTNR1A (0.46) | MAOAMAOBNFKB1MTNR1AMTNR1B | |
| SCHEMBL17086905 | 0.77 | MAOA (0.48) | MAOAMAOBNFKB1MTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017210072-A1 | ELECTROACTIVE COMPOUNDS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2017-12-07 | — | — | WO | disclosed |