Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.32 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.30 |
| ▸ | INSR | P06213 | 1/20 | 0.30 |
| ▸ | IGF1R | P08069 | 1/20 | 0.30 |
| ▸ | GBA1 | P04062 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19672683 | 0.72 | PTPN1 (0.33) | PTPN1 | |
| SCHEMBL20883322 | 0.70 | SLC6A2 (0.34) | KDM4ELMNA | |
| SCHEMBL19683586 | 0.70 | KDM4E (0.33) | KDM4ELMNAMAPTTHRBMAPK1 | |
| SCHEMBL20883313 | 0.68 | SLC6A2 (0.33) | KDM4ELMNA | |
| SCHEMBL19683685 | 0.67 | KDM4E (0.39) | KDM4EMAPTMTNR1APTPN1ACHE | |
| SCHEMBL19672624 | 0.66 | KDM4E (0.36) | KDM4ELMNAMAPTTHRBMAPK1 | |
| SCHEMBL20683148 | 0.65 | MET (0.32) | KDM4EMAPTMAPK1 | |
| SCHEMBL25030327 | 0.59 | HTR2A (0.42) | KDM4ELMNAMAPTMTNR1APTPN1 | |
| SCHEMBL8348726 | 0.56 | ADRB2 (0.71) | KDM4ELMNAMAPTMAPK1ACHE | |
| SCHEMBL6269458 | 0.56 | PTPN1 (0.57) | KDM4ELMNAMAPK1PTPN1ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017207519-A1 | PROCESS FOR OBTAINING 3,14-DIACETYLOXYMORPHONE FROM ORIPAVINE | ALCALIBER INVESTIGACIÓN DESARROLLO E INNOVACIÓN, S.L. (ES) | 2017-12-07 | — | — | WO | disclosed |