SCHEMBL19683685

SCHEMBL19683685

CNCCC1COc2c(OC(C)=O)ccc(C)c21

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.39
CYP3A4 P08684 1/20 0.34
PTPN1 P18031 1/20 0.33
ALDH1A1 P00352 2/20 0.33
GLA P06280 2/20 0.33
GAA P10253 2/20 0.33
MAPT P10636 2/20 0.33
HPGD P15428 2/20 0.33
CASP1 P29466 2/20 0.33
CASP7 P55210 2/20 0.33
HSD17B10 Q99714 2/20 0.33
HSP90AA1 P07900 1/20 0.33
HSP90AB1 P08238 1/20 0.33
ALPG P10696 1/20 0.33
ALOX15 P16050 1/20 0.33
ALOX12 P18054 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
SLC6A2 P23975 1/20 0.32
SLC6A4 P31645 1/20 0.32
SLC6A3 Q01959 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21098340 0.84 SLC6A2 (0.43) SLC6A2SLC6A4SLC6A3MTNR1AMTNR1B
SCHEMBL19683581 0.67 KDM4E (0.36) KDM4EPTPN1MAPTACHEMTNR1A
SCHEMBL18738025 0.65 HTR1A (0.32)
SCHEMBL25418795 0.60 FFAR1 (0.37)
SCHEMBL7713504 0.59 ALDH1A1 (0.51) CYP3A4PTPN1ALDH1A1GLAGAA
SCHEMBL7390252 0.59 ACHE (0.47) KDM4EPTPN1ALDH1A1GAAMAPT
SCHEMBL9328943 0.59 PTPN1 (0.62) KDM4EPTPN1ALDH1A1GAAMAPT
SCHEMBL25030327 0.59 HTR2A (0.42) KDM4EPTPN1ALDH1A1MAPTACHE
SCHEMBL11369330 0.58 CFD (0.43) KDM4ECYP3A4PTPN1ALDH1A1GAA
SCHEMBL11369326 0.58 CFD (0.43) KDM4ECYP3A4PTPN1ALDH1A1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2017207519-A1 PROCESS FOR OBTAINING 3,14-DIACETYLOXYMORPHONE FROM ORIPAVINE ALCALIBER INVESTIGACIÓN DESARROLLO E INNOVACIÓN, S.L. (ES) 2017-12-07 WO disclosed