Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.35 |
| ▸ | KDM4A | O75164 | 1/20 | 0.35 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.35 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4969707 | 0.90 | LMNA (0.41) | KDM4CKDM4APHF8KDM2ALMNA | |
| SCHEMBL10706313 | 0.82 | KDM4C (0.41) | KDM4CKDM4APHF8KDM2ALMNA | |
| SCHEMBL9494232 | 0.77 | — | — | |
| SCHEMBL4235434 | 0.76 | — | — | |
| SCHEMBL811655 | 0.76 | — | — | |
| SCHEMBL22753506 | 0.75 | LMNA (0.38) | LMNAALDH1A1 | |
| SCHEMBL10225592 | 0.75 | LMNA (0.38) | LMNAALDH1A1 | |
| SCHEMBL23209765 | 0.74 | DNM1 (0.37) | — | |
| SCHEMBL10706945 | 0.74 | KDM4C (0.42) | KDM4CKDM4APHF8KDM2ALMNA | |
| SCHEMBL15563088 | 0.74 | KDM4C (0.42) | KDM4CKDM4APHF8KDM2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017206962-A1 | NOVEL INHIBITOR FOR FLT3 KINASE AND USES THEREOF | 合肥中科普瑞昇生物医药科技有限公司 | 2017-12-07 | — | — | WO | disclosed |