Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 4/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.32 |
| ▸ | FAAH | O00519 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | XBP1 | P17861 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | MGLL | Q99685 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20197866 | 0.86 | PTGS1 (0.40) | PTGS1PTGS2ALDH1A1HSP90AA1TLR9 | |
| SCHEMBL26312049 | 0.86 | PTGS1 (0.56) | PTGS1PTGS2TSHRLMNASMN1; SMN2 | |
| SCHEMBL12629192 | 0.86 | PTGS1 (0.56) | PTGS1PTGS2TSHRLMNASMN1; SMN2 | |
| SCHEMBL24864496 | 0.84 | PTGS1 (0.39) | PTGS1PTGS2ALDH1A1TSHRHSP90AA1 | |
| SCHEMBL20442394 | 0.81 | ALDH1A1 (0.37) | PTGS1PTGS2ALDH1A1HPGDMAPK1 | |
| SCHEMBL13752367 | 0.81 | PTGS1 (0.36) | PTGS1PTGS2ALDH1A1HSP90AA1TLR9 | |
| SCHEMBL20840994 | 0.81 | PTGS1 (0.36) | PTGS1PTGS2ALDH1A1HSP90AA1TLR9 | |
| SCHEMBL23106441 | 0.81 | PTGS1 (0.36) | PTGS1PTGS2ALDH1A1HSP90AA1TLR9 | |
| SCHEMBL19683934 | 0.80 | PTGS1 (0.35) | PTGS1PTGS2ALDH1A1HSP90AA1TLR9 | |
| SCHEMBL19479764 | 0.79 | FAAH (0.36) | PTGS1PTGS2ALDH1A1FAAHHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11517625-B2 | Antibody-drug-conjugate and its use for the treatment of cancer | PIERRE FABRE MEDICAMENT (FR) | 2022-12-06 | — | — | US | disclosed |
| US-20210038738-A1 | ANTIBODY-DRUG-CONJUGATE AND ITS USE FOR THE TREATMENT OF CANCER | PIERRE FABRE MEDICAMENT (FR) | 2021-02-11 | — | — | US | disclosed |
| US-9901644-B2 | Dual acting prodrugs | KTB TUMORFORSCHUNGSGESELLSCHAFT MBH (DE) | 2018-02-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11517625-B2 | Antibody-drug-conjugate and its use for the treatment of cancer | DDOST, DAD1, KRTCAP2 | PTGS1 4290/4885PTGS2 4449/4885ALDH1A1 1223/4885 |
| US-20210038738-A1 | ANTIBODY-DRUG-CONJUGATE AND ITS USE FOR THE TREATMENT OF CANCER | DDOST, DAD1, KRTCAP2 | PTGS1 4193/4885PTGS2 4355/4885ALDH1A1 1110/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.