SCHEMBL19684276

SCHEMBL19684276

O=C1C(=Cc2ccc(N3c4ccsc4Sc4sccc43)s2)C(=O)c2ccccc21

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 10/20 0.49
KMT2A Q03164 6/20 0.49
ALDH1A1 P00352 6/20 0.49
HPGD P15428 3/20 0.49
RECQL P46063 2/20 0.49
TDP1 Q9NUW8 2/20 0.49
THRB P10828 1/20 0.49
NPSR1 Q6W5P4 1/20 0.49
HTT P42858 2/20 0.48
MEN1 O00255 4/20 0.42
RAB9A P51151 3/20 0.42
NPC1 O15118 2/20 0.42
EGFR P00533 1/20 0.37
RET P07949 1/20 0.37
KDR P35968 1/20 0.37
CTRC Q99895 1/20 0.37
POLB P06746 5/20 0.33
SMN1; SMN2 Q16637 4/20 0.33
NFKB1 P19838 2/20 0.33
NFKB2 Q00653 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19684272 0.90 ALDH1A1 (0.39) MAPTKMT2AALDH1A1HPGDRECQL
SCHEMBL19603607 0.84 MAPT (0.56) MAPTKMT2AALDH1A1HPGDRECQL
SCHEMBL19684273 0.83 ALDH1A1 (0.33) MAPTKMT2AALDH1A1HPGDRECQL
SCHEMBL19603584 0.83 MAPT (0.52) MAPTKMT2AALDH1A1HPGDRECQL
SCHEMBL19603592 0.80 MAPT (0.56) MAPTKMT2AALDH1A1HPGDRECQL
SCHEMBL19918312 0.80 KMT2A (0.52) MAPTKMT2AALDH1A1HPGDRECQL
SCHEMBL19684237 0.79 ALDH1A1 (0.30) MAPTKMT2AALDH1A1HPGDRECQL
SCHEMBL23345571 0.79 MAPT (0.51) MAPTKMT2AALDH1A1HPGDRECQL
SCHEMBL19603545 0.79 MAPT (0.51) MAPTKMT2AALDH1A1HPGDRECQL
SCHEMBL19603544 0.79 ALDH1A1 (0.51) MAPTKMT2AALDH1A1HPGDRECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10461256-B2 Compound and photoelectric device, image sensor and electronic device including the same SAMSUNG ELECTRONICS CO., LTD. (KR) 2019-10-29 US disclosed
US-20170352811-A1 COMPOUND AND PHOTOELECTRIC DEVICE, IMAGE SENSOR AND ELECTRONIC DEVICE INCLUDING THE SAME SAMSUNG ELECTRONICS CO., LTD. (KR) 2017-12-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10461256-B2 Compound and photoelectric device, image sensor and electronic device including the same NCS1, CRY1, CYP19A1 MAPT 3957/4885KMT2A 1372/4885ALDH1A1 22/4885
US-20170352811-A1 COMPOUND AND PHOTOELECTRIC DEVICE, IMAGE SENSOR AND ELECTRONIC DEVICE INCLUDING THE SAME NCS1, CRY1, CYP19A1 MAPT 3957/4885KMT2A 1372/4885ALDH1A1 22/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.