Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.55 |
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.39 |
| ▸ | MBTPS1 | Q14703 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | CHI3L1 | P36222 | 1/20 | 0.36 |
| ▸ | CHIT1 | Q13231 | 1/20 | 0.36 |
| ▸ | CHI3L2 | Q15782 | 1/20 | 0.36 |
| ▸ | CHIA | Q9BZP6 | 1/20 | 0.36 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27817763 | 0.81 | TAAR1 (0.62) | HTR2ATAAR1KDM4EGRIN2BSLC6A4 | |
| SCHEMBL2404071 | 0.81 | TAAR1 (0.62) | HTR2ATAAR1KDM4EGRIN2BSLC6A2 | |
| SCHEMBL1970014 | 0.81 | HTR2A (0.47) | HTR2ATAAR1KDM4EGRIN2BSLC6A4 | |
| SCHEMBL2405047 | 0.79 | TAAR1 (0.49) | HTR2ATAAR1KDM4EGRIN2BSLC6A4 | |
| SCHEMBL4711078 | 0.79 | L3MBTL1 (0.42) | HTR2ATAAR1KDM4EMBTPS1 | |
| SCHEMBL1965745 | 0.78 | AOC3 (0.61) | HTR2ATAAR1KCNH2 | |
| SCHEMBL3064865 | 0.77 | TAAR1 (0.61) | HTR2ATAAR1 | |
| SCHEMBL1967143 | 0.76 | GRIN2B (0.63) | HTR2ATAAR1KDM4EGRIN2BCHIA | |
| Hydrochloric Acid SCHEMBL28135517 | 0.75 | TAAR1 (0.59) | HTR2ATAAR1 | |
| SCHEMBL24776468 | 0.75 | HTR2A (0.55) | HTR2ATAAR1KDM4ESLC6A4SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110212968-A1 | PHENETHYLAMIDE DERIVATIVES AND THEIR HETEROCYCLIC ANALOGUES | ACTELION PHARMACEUTICALS LTD. (CH) | 2011-09-01 | — | — | US | disclosed |
| CN-102164896-A | Phenethylamide derivatives and their heterocyclic analogues | ACTELION PHARMACEUTICALS LTD | 2011-08-24 | — | — | CN | disclosed |
| EP-2334643-A1 | PHENETHYLAMIDE DERIVATIVES AND THEIR HETEROCYCLIC ANALOGUES | Actelion Pharmaceuticals Ltd. (CH) | 2011-06-22 | — | — | EP | disclosed |
| WO-2010044054-A1 | PHENETHYLAMIDE DERIVATIVES AND THEIR HETEROCYCLIC ANALOGUES | ACTELION PHARMACEUTICALS LTD (CH) | 2010-04-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110212968-A1 | PHENETHYLAMIDE DERIVATIVES AND THEIR HETEROCYCLIC ANALOGUES | HCRTR2, HCRTR1, HRH3 | HTR2A 46/4885TAAR1 48/4885KDM4E 452/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.