Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 1/20 | 0.31 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.31 |
| ▸ | NOS3 | P29474 | 1/20 | 0.31 |
| ▸ | NOS1 | P29475 | 1/20 | 0.31 |
| ▸ | NOS2 | P35228 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19132841 | 0.77 | NPC1 (0.32) | — | |
| SCHEMBL15595935 | 0.74 | — | — | |
| SCHEMBL20416958 | 0.74 | CCR1 (0.44) | NOS3NOS1NOS2 | |
| SCHEMBL24332991 | 0.72 | — | — | |
| SCHEMBL10391846 | 0.72 | NOS3 (0.46) | PDE2APDE10ANOS3NOS1NOS2 | |
| SCHEMBL15595934 | 0.71 | NOS3 (0.32) | NOS3NOS1NOS2 | |
| SCHEMBL12848429 | 0.70 | NOS3 (0.34) | PDE2APDE10ANOS3NOS1NOS2 | |
| SCHEMBL15966075 | 0.68 | ALDH1A1 (0.34) | PDE2APDE10ANOS3NOS1NOS2 | |
| SCHEMBL22431073 | 0.68 | TRPA1 (0.43) | PDE2APDE10ANOS3NOS1NOS2 | |
| SCHEMBL19913352 | 0.68 | NOS3 (0.42) | PDE2APDE10ANOS3NOS1NOS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017210694-A1 | TRIAZOLE BENZAMIDE DERIVATIVES AND THE COMPOSITIONS AND METHODS OF TREATMENT REGARDING THE SAME | An2H Discovery Limited (IE) | 2017-12-07 | — | — | WO | disclosed |