Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 1/20 | 0.45 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.45 |
| ▸ | AR | P10275 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | G6PD | P11413 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.36 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.34 |
| ▸ | CASP7 | P55210 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16256389 | 0.79 | GABRA1 (0.48) | GABRA1GABRB2ARPOLBSIGMAR1 | |
| SCHEMBL10699803 | 0.79 | AR (0.43) | GABRA1GABRB2ARMEN1POLB | |
| SCHEMBL29462975 | 0.79 | AR (0.49) | ARMEN1POLBKMT2AG6PD | |
| SCHEMBL4252040 | 0.79 | AR (0.49) | ARMEN1POLBKMT2AG6PD | |
| Bromide SCHEMBL9603071 | 0.78 | AR (0.42) | ARMEN1POLBKMT2AG6PD | |
| SCHEMBL23734263 | 0.78 | GABRA1 (0.52) | GABRA1GABRB2MEN1POLBKMT2A | |
| SCHEMBL6504953 | 0.78 | GABRA1 (0.47) | GABRA1GABRB2POLBSIGMAR1CA12 | |
| SCHEMBL22868422 | 0.77 | POLB (0.50) | ARMEN1POLBKMT2AG6PD | |
| SCHEMBL8679853 | 0.77 | ADRA2B (0.53) | ARMEN1POLBKMT2AG6PD | |
| Hydrochloric Acid SCHEMBL10475310 | 0.75 | GRIN2D (0.39) | ARMEN1POLBKMT2AG6PD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017210694-A1 | TRIAZOLE BENZAMIDE DERIVATIVES AND THE COMPOSITIONS AND METHODS OF TREATMENT REGARDING THE SAME | An2H Discovery Limited (IE) | 2017-12-07 | — | — | WO | disclosed |