Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 1/20 | 0.47 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | NOS3 | P29474 | 1/20 | 0.40 |
| ▸ | NOS1 | P29475 | 1/20 | 0.40 |
| ▸ | NOS2 | P35228 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA6 | P23280 | 1/20 | 0.35 |
| ▸ | CA5A | P35218 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28046225 | 0.82 | GABRA1 (0.47) | GABRA1GABRB2ALDH1A1GAAMAPT | |
| SCHEMBL6940133 | 0.81 | AOC3 (0.52) | NOS3NOS1NOS2L3MBTL1AOC3 | |
| SCHEMBL16256389 | 0.81 | GABRA1 (0.48) | GABRA1GABRB2ALDH1A1MAPTNOS3 | |
| SCHEMBL6938711 | 0.80 | ALDH1A1 (0.42) | ALDH1A1GAAMAPTNOS3NOS1 | |
| SCHEMBL6937591 | 0.80 | SLC6A2 (0.42) | ALDH1A1GAAMAPTL3MBTL1POLB | |
| SCHEMBL11919003 | 0.80 | L3MBTL1 (0.49) | GABRA1GABRB2ALDH1A1GAAMAPT | |
| SCHEMBL6940084 | 0.80 | TAS1R3 (0.42) | ALDH1A1GAAMAPTNOS3NOS1 | |
| SCHEMBL23734263 | 0.79 | GABRA1 (0.52) | GABRA1GABRB2ALDH1A1MAPTNOS3 | |
| SCHEMBL19685425 | 0.78 | GABRA1 (0.45) | GABRA1GABRB2ALDH1A1MAPTL3MBTL1 | |
| SCHEMBL11440473 | 0.77 | L3MBTL1 (0.53) | GABRA1GABRB2ALDH1A1GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005040127-A1 | NOVEL COMPOUNDS AS AGONIST FOR PPAR GAMMA AND PPAR ALPHA, METHOD FOR PREPARATION OF THE SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | LG LIFE SCIENCES LTD. (KR) | 2005-05-06 | — | — | WO | disclosed |
| EP-1272456-A1 | HYDRAZIDE AND ALKOXYAMIDE ANGIOGENESIS INHIBITORS | Abbott Laboratories (US) | 2003-01-08 | — | — | EP | disclosed |
| WO-2001079157-A1 | HYDRAZIDE AND ALKOXYAMIDE ANGIOGENESIS INHIBITORS | ABBOTT LABORATORIES (US) | 2001-10-25 | — | — | WO | disclosed |