Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 4/20 | 0.37 |
| ▸ | APP | P05067 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18968249 | 0.84 | ALDH1A1 (0.36) | HPGDCYP1A2CYP2C19BCHEAPP | |
| SCHEMBL7560809 | 0.76 | LMNA (0.43) | LMNAHPGDCYP1A2PTGS1SLC6A2 | |
| SCHEMBL7561778 | 0.75 | CYP2C19 (0.41) | LMNACYP1A2PTGS1SLC6A2CYP2C19 | |
| SCHEMBL7562101 | 0.73 | ALDH1A1 (0.45) | LMNAHPGDCYP1A2PTGS1SLC6A2 | |
| SCHEMBL10689679 | 0.72 | HTR1A (0.48) | LMNAHPGDCYP1A2PTGS1SLC6A2 | |
| SCHEMBL4238441 | 0.71 | CYP2C19 (0.42) | LMNACYP1A2PTGS1SLC6A2CYP2C19 | |
| SCHEMBL16684894 | 0.71 | ALOX5AP (0.41) | LMNAHPGDCYP1A2CYP2C19BCHE | |
| SCHEMBL18960826 | 0.71 | PTPN1 (0.43) | LMNAHPGDBCHEHTR1AADRA1D | |
| SCHEMBL877466 | 0.70 | PDE5A (0.41) | LMNACYP1A2PTGS1SLC6A2CYP2C19 | |
| SCHEMBL2030039 | 0.70 | ALDH1A1 (0.60) | LMNAHPGDPTGS1APPALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170347654-A1 | Herbicidal Compounds | SYNGENTA PARTICIPATIONS AG (CH) | 2017-12-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170347654-A1 | Herbicidal Compounds | DDT, GLRX3, AGXT | LMNA 2013/4885HPGD 434/4885CYP1A2 89/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.