SCHEMBL19685722

SCHEMBL19685722

Cc1cn(C)c(=O)c2ccc(-c3ccc(N(c4ccccc4)c4ccccc4)cc3)cc12

nearest known ligand 0.53

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
BRD4 O60885 15/20 0.53
BRD9 Q9H8M2 2/20 0.43
BRD7 Q9NPI1 1/20 0.43
MAPT P10636 1/20 0.40
TNKS2 Q9H2K2 1/20 0.38
POLB P06746 1/20 0.38
MEN1 O00255 1/20 0.37
KMT2A Q03164 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19685725 0.95 BRD4 (0.50) BRD4BRD9BRD7MAPTTNKS2
SCHEMBL19685728 0.90 BRD4 (0.45) BRD4BRD9BRD7MAPTPOLB
SCHEMBL19685727 0.85 BRD4 (0.43) BRD4BRD9BRD7MAPTPOLB
SCHEMBL19686145 0.84 KDM4E (0.40) BRD4TNKS2
SCHEMBL19686030 0.80 NR4A2 (0.45) BRD4MAPTPOLBMEN1KMT2A
SCHEMBL19685961 0.80 BRD4 (0.39) BRD4TNKS2POLB
SCHEMBL19685723 0.79 BRD4 (0.36) BRD4BRD9BRD7MAPTPOLB
SCHEMBL19686044 0.79 TNKS2 (0.39) BRD4TNKS2
SCHEMBL19685731 0.77 BRD4 (0.52) BRD4BRD9BRD7TNKS2
SCHEMBL19686028 0.74 APP (0.35) BRD4BRD9BRD7MAPTPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10714693-B2 Polycyclic compound and organic electroluminescence device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2020-07-14 US disclosed
US-20170352817-A1 POLYCYCLIC COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE INCLUDING THE SAME KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) 2017-12-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10714693-B2 Polycyclic compound and organic electroluminescence device including the same CYC1, CCNA1, CYCS BRD4 740/4885BRD9 1480/4885BRD7 2005/4885
US-20170352817-A1 POLYCYCLIC COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE INCLUDING THE SAME CYC1, CCNA1, CYCS BRD4 740/4885BRD9 1480/4885BRD7 2005/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.