SCHEMBL19686028

SCHEMBL19686028

Cc1cn(C)c(=O)c2cc(-n3c4ccc(N(c5ccccc5)c5ccccc5)cc4c4cc(N(c5ccccc5)c5ccccc5)ccc43)ccc12

nearest known ligand 0.35

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
APP P05067 1/20 0.35
BRD4 O60885 9/20 0.35
MAPT P10636 2/20 0.34
BRD9 Q9H8M2 1/20 0.33
BRD7 Q9NPI1 1/20 0.33
POLB P06746 2/20 0.32
CREBBP Q92793 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
SMN1; SMN2 Q16637 2/20 0.32
LMNA P02545 1/20 0.32
HPGD P15428 1/20 0.32
HTT P42858 1/20 0.32
PKM P14618 1/20 0.31
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31
ALDH1A1 P00352 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19685723 0.95 BRD4 (0.36) APPBRD4MAPTBRD9BRD7
SCHEMBL19685727 0.88 BRD4 (0.43) APPBRD4MAPTBRD9BRD7
SCHEMBL19685830 0.88 APP (0.34) APPMAPTPOLBSMN1; SMN2LMNA
SCHEMBL19686281 0.85 APP (0.36) APPBRD4MAPTPOLBSMN1; SMN2
SCHEMBL19685726 0.84 BRD4 (0.42) BRD4MAPTBRD9BRD7POLB
SCHEMBL19685967 0.84 APP (0.35) APPPOLBSMN1; SMN2PKMMEN1
SCHEMBL19686344 0.83 ESR1 (0.36) APPMAPTPOLBSMN1; SMN2LMNA
SCHEMBL19685728 0.83 BRD4 (0.45) APPBRD4MAPTBRD9BRD7
SCHEMBL19686027 0.82 BRD4 (0.49) BRD4BRD9BRD7ALDH1A1
SCHEMBL19685855 0.80 APP (0.35) APPMAPTPOLBSMN1; SMN2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10714693-B2 Polycyclic compound and organic electroluminescence device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2020-07-14 US disclosed
US-20170352817-A1 POLYCYCLIC COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE INCLUDING THE SAME KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) 2017-12-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10714693-B2 Polycyclic compound and organic electroluminescence device including the same CYC1, CCNA1, CYCS APP 2048/4885BRD4 740/4885MAPT 4713/4885
US-20170352817-A1 POLYCYCLIC COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE INCLUDING THE SAME CYC1, CCNA1, CYCS APP 2048/4885BRD4 740/4885MAPT 4713/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.