SCHEMBL19685728

SCHEMBL19685728

Cc1cn(C)c(=O)c2ccc(N(c3ccccc3)c3ccccc3)cc12

nearest known ligand 0.45

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
BRD4 O60885 15/20 0.45
BRD9 Q9H8M2 1/20 0.43
BRD7 Q9NPI1 1/20 0.43
MAPT P10636 1/20 0.43
POLB P06746 1/20 0.40
MEN1 O00255 1/20 0.39
KMT2A Q03164 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
APP P05067 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19685727 0.94 BRD4 (0.43) BRD4BRD9BRD7MAPTPOLB
SCHEMBL19685722 0.90 BRD4 (0.53) BRD4BRD9BRD7MAPTPOLB
SCHEMBL19685723 0.88 BRD4 (0.36) BRD4BRD9BRD7MAPTPOLB
SCHEMBL19685725 0.85 BRD4 (0.50) BRD4BRD9BRD7MAPT
SCHEMBL19686144 0.83 KDM4E (0.42) KMT2AAPP
SCHEMBL19686028 0.83 APP (0.35) BRD4BRD9BRD7MAPTPOLB
SCHEMBL19685960 0.78 PKM (0.36) BRD4APP
SCHEMBL19685820 0.78 KMT2A (0.39) BRD4MAPTPOLBMEN1KMT2A
SCHEMBL19686045 0.77 KDM4E (0.39) KMT2AAPP
SCHEMBL147301 0.75 BRD4 (0.67) BRD4BRD9BRD7POLBL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10714693-B2 Polycyclic compound and organic electroluminescence device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2020-07-14 US disclosed
US-20170352817-A1 POLYCYCLIC COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE INCLUDING THE SAME KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) 2017-12-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10714693-B2 Polycyclic compound and organic electroluminescence device including the same CYC1, CCNA1, CYCS BRD4 740/4885BRD9 1480/4885BRD7 2005/4885
US-20170352817-A1 POLYCYCLIC COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE INCLUDING THE SAME CYC1, CCNA1, CYCS BRD4 740/4885BRD9 1480/4885BRD7 2005/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.