SCHEMBL19685850

SCHEMBL19685850

Cc1coc(=O)c2ccc(-n3c4ccccc4c4cc(-n5c6ccccc6c6ccccc65)ccc43)cc12

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 5/20 0.38
ATM Q13315 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
MAPT P10636 6/20 0.36
MEN1 O00255 5/20 0.36
KMT2A Q03164 5/20 0.36
ALDH1A1 P00352 4/20 0.36
NPSR1 Q6W5P4 2/20 0.36
USP2 O75604 1/20 0.36
ALPI P09923 1/20 0.36
POLB P06746 4/20 0.36
RECQL P46063 1/20 0.36
NQO2 P16083 1/20 0.35
LMNA P02545 3/20 0.35
THRB P10828 1/20 0.34
CYP1A2 P05177 1/20 0.34
CYP3A4 P08684 1/20 0.34
CYP2D6 P10635 1/20 0.34
CYP2C9 P11712 1/20 0.34
CYP2C19 P33261 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19685804 0.95 KDM4E (0.38) KDM4EATML3MBTL1MAPTMEN1
SCHEMBL19685853 0.87 TNKS2 (0.37) EDNRBEDNRA
SCHEMBL19685851 0.84 APP (0.35) L3MBTL1MAPTALDH1A1NPSR1POLB
SCHEMBL19685903 0.82 KDM4E (0.40) KDM4EATML3MBTL1MAPTMEN1
SCHEMBL19685688 0.80 PDE10A (0.38) KDM4EATML3MBTL1ALDH1A1NQO2
SCHEMBL19685855 0.79 APP (0.35) MAPTALDH1A1NPSR1POLBLMNA
SCHEMBL19685729 0.76 BRD4 (0.46) KDM4EATML3MBTL1POLBNQO2
SCHEMBL17915764 0.74 KDM4E (0.56) KDM4EATML3MBTL1MAPTMEN1
SCHEMBL17915742 0.74 KDM4E (0.56) KDM4EATML3MBTL1MAPTMEN1
SCHEMBL10450007 0.74 KDM4E (0.56) KDM4EATML3MBTL1MAPTMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10714693-B2 Polycyclic compound and organic electroluminescence device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2020-07-14 US disclosed
US-20170352817-A1 POLYCYCLIC COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE INCLUDING THE SAME KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) 2017-12-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10714693-B2 Polycyclic compound and organic electroluminescence device including the same CYC1, CCNA1, CYCS KDM4E 1138/4885ATM 4045/4885L3MBTL1 2451/4885
US-20170352817-A1 POLYCYCLIC COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE INCLUDING THE SAME CYC1, CCNA1, CYCS KDM4E 1138/4885ATM 4045/4885L3MBTL1 2451/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.