Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | GFER | P55789 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19685851 | 0.95 | APP (0.35) | APPSMN1; SMN2HTTLMNAHPGD | |
| SCHEMBL19685799 | 0.87 | ALDH1A1 (0.35) | APPHPGDMAPTALDH1A1GAA | |
| SCHEMBL19685804 | 0.84 | KDM4E (0.38) | LMNAMAPTALDH1A1NPSR1POLB | |
| SCHEMBL19686136 | 0.83 | ALDH1A1 (0.37) | APPALDH1A1 | |
| SCHEMBL19685893 | 0.83 | ALDH1A1 (0.36) | APPSMN1; SMN2HTTHPGDMAPT | |
| SCHEMBL19686110 | 0.81 | ALDH1A1 (0.38) | APPHPGDMAPTALDH1A1NPSR1 | |
| SCHEMBL19686028 | 0.80 | APP (0.35) | APPSMN1; SMN2HTTLMNAHPGD | |
| SCHEMBL19685850 | 0.79 | KDM4E (0.38) | LMNAMAPTALDH1A1NPSR1POLB | |
| SCHEMBL19685830 | 0.79 | APP (0.34) | APPSMN1; SMN2HTTLMNAHPGD | |
| SCHEMBL19685853 | 0.78 | TNKS2 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10714693-B2 | Polycyclic compound and organic electroluminescence device including the same | SAMSUNG DISPLAY CO., LTD. (KR) | 2020-07-14 | — | — | US | disclosed |
| US-20170352817-A1 | POLYCYCLIC COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE INCLUDING THE SAME | KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) | 2017-12-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10714693-B2 | Polycyclic compound and organic electroluminescence device including the same | CYC1, CCNA1, CYCS | APP 2048/4885SMN1; SMN2 4348/4885HTT 1355/4885 |
| US-20170352817-A1 | POLYCYCLIC COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE INCLUDING THE SAME | CYC1, CCNA1, CYCS | APP 2048/4885SMN1; SMN2 4348/4885HTT 1355/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.