SCHEMBL19685862

SCHEMBL19685862

Cc1ccc2c(c1)C1(c3ccccc3-c3ccccc31)c1cc(C)ccc1N2c1ccc2c(=O)c(C)cn(C)c2c1

nearest known ligand 0.36

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
TP53 P04637 2/20 0.35
PKM P14618 1/20 0.34
CNR1 P21554 1/20 0.34
GPR55 Q9Y2T6 1/20 0.34
PGR P06401 1/20 0.33
PRKCA P17252 1/20 0.32
GSK3B P49841 1/20 0.32
MEN1 O00255 2/20 0.32
KMT2A Q03164 2/20 0.32
MAPT P10636 2/20 0.32
NPC1 O15118 1/20 0.32
RAB9A P51151 1/20 0.32
NTRK1 P04629 1/20 0.31
THRB P10828 2/20 0.31
MAOB P27338 1/20 0.31
ALDH1A1 P00352 1/20 0.31
ADAMTS5 Q9UNA0 1/20 0.31
PDK2 Q15119 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19685817 0.92 TP53 (0.35) TP53PKMCNR1GPR55PGR
SCHEMBL19685736 0.91 MEN1 (0.35) TP53PGRMEN1KMT2AMAOB
SCHEMBL19685865 0.89 TP53 (0.34) TP53PKMCNR1GPR55MEN1
SCHEMBL19686033 0.88 PGR (0.32) TP53PKMCNR1GPR55PGR
SCHEMBL19686081 0.84 BRD4 (0.40) TP53PKMCNR1GPR55PGR
SCHEMBL19686022 0.84 BRD4 (0.37) TP53PKMCNR1GPR55PGR
SCHEMBL19685812 0.83 MGAM (0.37) MEN1KMT2AMAPTNPC1RAB9A
SCHEMBL19685866 0.82 MEN1 (0.32) MEN1KMT2AMAPTNPC1RAB9A
SCHEMBL19686169 0.82 SCN2B (0.34) TP53PKMCNR1GPR55PGR
SCHEMBL19685821 0.81 TP53 (0.34) TP53PKMCNR1GPR55MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10714693-B2 Polycyclic compound and organic electroluminescence device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2020-07-14 US disclosed
US-20170352817-A1 POLYCYCLIC COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE INCLUDING THE SAME KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) 2017-12-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10714693-B2 Polycyclic compound and organic electroluminescence device including the same CYC1, CCNA1, CYCS TP53 1993/4885PKM 1499/4885CNR1 32/4885
US-20170352817-A1 POLYCYCLIC COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE INCLUDING THE SAME CYC1, CCNA1, CYCS TP53 1993/4885PKM 1499/4885CNR1 32/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.