SCHEMBL19685866

SCHEMBL19685866

Cc1cn(C)c2cc(N3c4ccccc4C4(c5ccccc5Sc5ccccc54)c4ccccc43)ccc2c1=O

nearest known ligand 0.32

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.32
NPC1 O15118 2/20 0.32
MAPT P10636 2/20 0.32
RAB9A P51151 2/20 0.32
KMT2A Q03164 2/20 0.32
EGLN1 Q9GZT9 1/20 0.31
MGAM O43451 1/20 0.31
GAA P10253 1/20 0.31
SI P14410 1/20 0.31
MGAM2 Q2M2H8 1/20 0.31
MAPK1 P28482 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19685818 0.92 MGAM (0.35) MEN1NPC1MAPTRAB9AKMT2A
SCHEMBL19685736 0.88 MEN1 (0.35) MEN1KMT2AEGLN1MGAMGAA
SCHEMBL19685925 0.88 MAPK8 (0.32)
SCHEMBL19685732 0.86 EGLN1 (0.32) EGLN1MGAMGAASIMGAM2
SCHEMBL19685864 0.85 EGLN1 (0.31) EGLN1MGAMGAASIMGAM2
SCHEMBL19685730 0.84 BRD4 (0.33) EGLN1
SCHEMBL19686084 0.84 BRD4 (0.35) EGLN1
SCHEMBL19685867 0.84 MEN1 (0.35) MEN1NPC1MAPTRAB9AKMT2A
SCHEMBL19685862 0.82 TP53 (0.35) MEN1NPC1MAPTRAB9AKMT2A
SCHEMBL19685977 0.81 SCN2B (0.34)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10714693-B2 Polycyclic compound and organic electroluminescence device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2020-07-14 US disclosed
US-20170352817-A1 POLYCYCLIC COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE INCLUDING THE SAME KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) 2017-12-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10714693-B2 Polycyclic compound and organic electroluminescence device including the same CYC1, CCNA1, CYCS MEN1 644/4885NPC1 4513/4885MAPT 4713/4885
US-20170352817-A1 POLYCYCLIC COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE INCLUDING THE SAME CYC1, CCNA1, CYCS MEN1 644/4885NPC1 4513/4885MAPT 4713/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.