SCHEMBL19686084

SCHEMBL19686084

Cc1cn(C)c(=O)c2ccc(N3c4ccccc4C4(c5ccccc5Sc5ccccc54)c4ccccc43)cc12

nearest known ligand 0.35

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
BRD4 O60885 7/20 0.35
BRD9 Q9H8M2 1/20 0.34
BRD7 Q9NPI1 1/20 0.34
EGLN1 Q9GZT9 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.30
POLB P06746 1/20 0.30
HDAC6 Q9UBN7 1/20 0.30
MAOA P21397 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19685730 0.96 BRD4 (0.33) BRD4BRD9BRD7EGLN1HDAC6
SCHEMBL19685860 0.88 BRD4 (0.43) BRD4BRD9BRD7EGLN1
SCHEMBL19686148 0.87 ESR1 (0.34)
SCHEMBL19685857 0.85 BRD4 (0.37) BRD4BRD9BRD7EGLN1L3MBTL1
SCHEMBL19686082 0.85 BRD4 (0.35) BRD4BRD9BRD7EGLN1L3MBTL1
SCHEMBL19685866 0.84 MEN1 (0.32) EGLN1
SCHEMBL19685818 0.84 MGAM (0.35) EGLN1
SCHEMBL19686024 0.83 BRD4 (0.40) BRD4BRD9BRD7EGLN1
SCHEMBL19686080 0.83 BRD4 (0.43) BRD4BRD9BRD7
SCHEMBL19686134 0.83 ESR1 (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10714693-B2 Polycyclic compound and organic electroluminescence device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2020-07-14 US disclosed
US-20170352817-A1 POLYCYCLIC COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE INCLUDING THE SAME KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) 2017-12-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10714693-B2 Polycyclic compound and organic electroluminescence device including the same CYC1, CCNA1, CYCS BRD4 740/4885BRD9 1480/4885BRD7 2005/4885
US-20170352817-A1 POLYCYCLIC COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE INCLUDING THE SAME CYC1, CCNA1, CYCS BRD4 740/4885BRD9 1480/4885BRD7 2005/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.